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Cost-Neutral Optimization of Pazopanib Exposure by Splitting Intake Moments: A Prospective Pharmacokinetic Study in Cancer Patients.
Groenland, Stefanie L; van Eerden, Ruben A G; Verheijen, Remy B; de Vries, Niels; Thijssen, Bas; Rosing, Hilde; Beijnen, Jos H; Koolen, Stijn L W; Mathijssen, Ron H J; Huitema, Alwin D R; Steeghs, Neeltje.
Afiliação
  • Groenland SL; Division of Medical Oncology, Department of Clinical Pharmacology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands. s.groenland@nki.nl.
  • van Eerden RAG; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
  • Verheijen RB; Department of Pharmacy and Pharmacology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek, Amsterdam, The Netherlands.
  • de Vries N; Department of Pharmacy and Pharmacology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek, Amsterdam, The Netherlands.
  • Thijssen B; Department of Pharmacy and Pharmacology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek, Amsterdam, The Netherlands.
  • Rosing H; Department of Pharmacy and Pharmacology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek, Amsterdam, The Netherlands.
  • Beijnen JH; Department of Pharmacy and Pharmacology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek, Amsterdam, The Netherlands.
  • Koolen SLW; Department of Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.
  • Mathijssen RHJ; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
  • Huitema ADR; Department of Hospital Pharmacy, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Steeghs N; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
Clin Pharmacokinet ; 59(7): 941-948, 2020 07.
Article em En | MEDLINE | ID: mdl-32020530

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Sulfonamidas / Carcinoma de Células Renais / Indazóis / Neoplasias Renais Tipo de estudo: Clinical_trials / Health_economic_evaluation / Observational_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Clin Pharmacokinet Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Holanda

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Sulfonamidas / Carcinoma de Células Renais / Indazóis / Neoplasias Renais Tipo de estudo: Clinical_trials / Health_economic_evaluation / Observational_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Clin Pharmacokinet Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Holanda