Your browser doesn't support javascript.
loading
Longitudinal Trajectories of Hemodynamics Following Left Ventricular Assist Device Implantation.
Fujino, Takeo; Sayer, Aline; Nitta, Daisuke; Imamura, Teruhiko; Narang, Nikhil; Nguyen, Ann; Rodgers, Daniel; Raikhelkar, Jayant; Smith, Bryan; Kim, Gene; LaBuhn, Colleen; Jeevanandam, Valluvan; Burkhoff, Daniel; Sayer, Gabriel; Uriel, Nir.
Afiliação
  • Fujino T; Department of Medicine, University of Chicago Medical Center, 5841 S. Maryland Avenue, Chicago, IL 60637, USA.
  • Sayer A; Department of Medicine, University of Chicago Medical Center, 5841 S. Maryland Avenue, Chicago, IL 60637, USA.
  • Nitta D; Department of Medicine, University of Chicago Medical Center, 5841 S. Maryland Avenue, Chicago, IL 60637, USA.
  • Imamura T; Department of Medicine, University of Chicago Medical Center, 5841 S. Maryland Avenue, Chicago, IL 60637, USA.
  • Narang N; Department of Medicine, University of Chicago Medical Center, 5841 S. Maryland Avenue, Chicago, IL 60637, USA.
  • Nguyen A; Department of Medicine, University of Chicago Medical Center, 5841 S. Maryland Avenue, Chicago, IL 60637, USA.
  • Rodgers D; Department of Medicine, University of Chicago Medical Center, 5841 S. Maryland Avenue, Chicago, IL 60637, USA.
  • Raikhelkar J; Department of Surgery, University of Chicago Medical Center, 5841 S. Maryland Avenue, Chicago, IL 60637, USA.
  • Smith B; Department of Medicine, University of Chicago Medical Center, 5841 S. Maryland Avenue, Chicago, IL 60637, USA.
  • Kim G; Department of Medicine, University of Chicago Medical Center, 5841 S. Maryland Avenue, Chicago, IL 60637, USA.
  • LaBuhn C; Department of Cardiology, Columbia University Irving Medical Center, 622 W. 168th Street, New York, NY 10032, USA.
  • Jeevanandam V; Department of Cardiology, Columbia University Irving Medical Center, 622 W. 168th Street, New York, NY 10032, USA.
  • Burkhoff D; Department of Surgery, University of Chicago Medical Center, 5841 S. Maryland Avenue, Chicago, IL 60637, USA.
  • Sayer G; Department of Surgery, University of Chicago Medical Center, 5841 S. Maryland Avenue, Chicago, IL 60637, USA.
  • Uriel N; Department of Surgery, University of Chicago Medical Center, 5841 S. Maryland Avenue, Chicago, IL 60637, USA; Columbia University Medical Center, and Cardiovascular Research Foundation, 1700 Broadway, New York, NY 10019, USA. Electronic address: nuriel@medicine.bsd.uchicago.edu.
J Card Fail ; 26(5): 383-390, 2020 May.
Article em En | MEDLINE | ID: mdl-32027961
ABSTRACT

BACKGROUND:

Continuous-flow left ventricular assist devices (LVADs) improve the hemodynamics of patients with advanced heart failure. However, the longitudinal trajectories of hemodynamics in patients after LVAD implantation remain unknown. The aim of this study was to investigate the trends of hemodynamic parameters following LVAD implantation. METHODS AND

RESULTS:

We retrospectively reviewed patients who underwent LVAD implantation between April 2014 and August 2018. We collected hemodynamic parameters from right heart catheterizations. Of 199 consecutive patients, we enrolled 150 patients who had both pre- and postimplant right heart catheterizations. They had 3 (2, 4) postimplant right heart catheterizations during a follow-up of 2.3 (1.3, 3.1) years. The mean age was 57 ± 13 years, and 102 patients (68%) were male. Following LVAD implantation, pulmonary arterial pressure and pulmonary capillary wedge pressure decreased, and cardiac index increased significantly, then remained unchanged throughout follow-up. Right atrial pressure decreased initially and then gradually increased to preimplant values. The pulmonary artery pulsatility index decreased initially and returned to preimplant values, then progressively decreased over longer follow-up. Subgroup analysis showed significant differences in the trajectories of the pulmonary artery pulsatility index based on gender.

CONCLUSIONS:

Despite improvement in left-side filling pressures and cardiac index following LVAD implantation, right atrial pressure increased and the pulmonary artery pulsatility index decreased over time, suggesting progressive right ventricular dysfunction.
Assuntos
Palavras-chave

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Coração Auxiliar / Disfunção Ventricular Direita / Insuficiência Cardíaca Tipo de estudo: Observational_studies Limite: Humans / Male / Middle aged Idioma: En Revista: J Card Fail Assunto da revista: CARDIOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Coração Auxiliar / Disfunção Ventricular Direita / Insuficiência Cardíaca Tipo de estudo: Observational_studies Limite: Humans / Male / Middle aged Idioma: En Revista: J Card Fail Assunto da revista: CARDIOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos