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Selective inhibition of Ph-positive ALL cell growth through kinase-dependent and -independent effects by CDK6-specific PROTACs.
De Dominici, Marco; Porazzi, Patrizia; Xiao, Youcai; Chao, Allen; Tang, Hsin-Yao; Kumar, Gaurav; Fortina, Paolo; Spinelli, Orietta; Rambaldi, Alessandro; Peterson, Luke F; Petruk, Svetlana; Barletta, Camilla; Mazo, Alexander; Cingolani, Gino; Salvino, Joseph M; Calabretta, Bruno.
Afiliação
  • De Dominici M; Department of Cancer Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA.
  • Porazzi P; Department of Cancer Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA.
  • Xiao Y; The Wistar Institute, Philadelphia, PA.
  • Chao A; The Wistar Institute, Philadelphia, PA.
  • Tang HY; The Wistar Institute, Philadelphia, PA.
  • Kumar G; Department of Cancer Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA.
  • Fortina P; Department of Cancer Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA.
  • Spinelli O; Hematology and Bone Marrow Transplant Unit, Ospedale Papa Giovanni XXIII, Bergamo, Italy.
  • Rambaldi A; Hematology and Bone Marrow Transplant Unit, Ospedale Papa Giovanni XXIII, Bergamo, Italy.
  • Peterson LF; Department of Oncology and Hematology-Oncology, Università Statale Milano, Milan, Italy.
  • Petruk S; Department of Internal Medicine, University of Michigan, Ann Arbor, MI; and.
  • Barletta C; Department of Biochemistry and Molecular Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA.
  • Mazo A; Department of Cancer Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA.
  • Cingolani G; Department of Biochemistry and Molecular Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA.
  • Salvino JM; Department of Biochemistry and Molecular Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA.
  • Calabretta B; The Wistar Institute, Philadelphia, PA.
Blood ; 135(18): 1560-1573, 2020 04 30.
Article em En | MEDLINE | ID: mdl-32040545
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Recombinantes de Fusão / Inibidores de Proteínas Quinases / Quinase 6 Dependente de Ciclina / Leucemia-Linfoma Linfoblástico de Células Precursoras Tipo de estudo: Etiology_studies Limite: Animals / Humans Idioma: En Revista: Blood Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Panamá
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Recombinantes de Fusão / Inibidores de Proteínas Quinases / Quinase 6 Dependente de Ciclina / Leucemia-Linfoma Linfoblástico de Células Precursoras Tipo de estudo: Etiology_studies Limite: Animals / Humans Idioma: En Revista: Blood Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Panamá