Novel ESCC-related gene ZNF750 as potential Prognostic biomarker and inhibits Epithelial-Mesenchymal Transition through directly depressing SNAI1 promoter in ESCC.

Kong, Pengzhou; Xu, Enwei; Bi, Yanghui; Xu, Xiaoqin; Liu, Xue; Song, Bin; Zhang, Ling; Cheng, Caixia; Yan, Ting; Qian, Yu; Yang, Jian; Ma, Yanchun; Cui, Heyang; Zhai, Yuanfang; Zou, Binbin; Liu, Xiangchen; Cheng, Yikun; Guo, Shiping; Cheng, Xiaolong; Cui, Yongping

Kong, Pengzhou; Xu, Enwei; Bi, Yanghui; Xu, Xiaoqin; Liu, Xue; Song, Bin; Zhang, Ling; Cheng, Caixia; Yan, Ting; Qian, Yu; Yang, Jian; Ma, Yanchun; Cui, Heyang; Zhai, Yuanfang; Zou, Binbin; Liu, Xiangchen; Cheng, Yikun; Guo, Shiping; Cheng, Xiaolong; Cui, Yongping.

Afiliação

Kong P; Department of Pathology & Shanxi Key Laboratory of Carcinogenesis and Translational Research on Esophageal Cancer, Shanxi Medical University, Taiyuan, Shanxi 030001 P. R. China.
Xu E; Department of Pathology & Shanxi Key Laboratory of Carcinogenesis and Translational Research on Esophageal Cancer, Shanxi Medical University, Taiyuan, Shanxi 030001 P. R. China.
Bi Y; Department of Pathology & Shanxi Key Laboratory of Carcinogenesis and Translational Research on Esophageal Cancer, Shanxi Medical University, Taiyuan, Shanxi 030001 P. R. China.
Xu X; Department of Pathology & Shanxi Key Laboratory of Carcinogenesis and Translational Research on Esophageal Cancer, Shanxi Medical University, Taiyuan, Shanxi 030001 P. R. China.
Liu X; Department of Pathology & Shanxi Key Laboratory of Carcinogenesis and Translational Research on Esophageal Cancer, Shanxi Medical University, Taiyuan, Shanxi 030001 P. R. China.
Song B; Department of Pathology & Shanxi Key Laboratory of Carcinogenesis and Translational Research on Esophageal Cancer, Shanxi Medical University, Taiyuan, Shanxi 030001 P. R. China.
Zhang L; Department of Pathology & Shanxi Key Laboratory of Carcinogenesis and Translational Research on Esophageal Cancer, Shanxi Medical University, Taiyuan, Shanxi 030001 P. R. China.
Cheng C; Department of Pathology & Shanxi Key Laboratory of Carcinogenesis and Translational Research on Esophageal Cancer, Shanxi Medical University, Taiyuan, Shanxi 030001 P. R. China.
Yan T; Department of Pathology & Shanxi Key Laboratory of Carcinogenesis and Translational Research on Esophageal Cancer, Shanxi Medical University, Taiyuan, Shanxi 030001 P. R. China.
Qian Y; Department of Pathology & Shanxi Key Laboratory of Carcinogenesis and Translational Research on Esophageal Cancer, Shanxi Medical University, Taiyuan, Shanxi 030001 P. R. China.
Yang J; Department of Pathology & Shanxi Key Laboratory of Carcinogenesis and Translational Research on Esophageal Cancer, Shanxi Medical University, Taiyuan, Shanxi 030001 P. R. China.
Ma Y; Department of Pathology & Shanxi Key Laboratory of Carcinogenesis and Translational Research on Esophageal Cancer, Shanxi Medical University, Taiyuan, Shanxi 030001 P. R. China.
Cui H; Department of Pathology & Shanxi Key Laboratory of Carcinogenesis and Translational Research on Esophageal Cancer, Shanxi Medical University, Taiyuan, Shanxi 030001 P. R. China.
Zhai Y; Department of Pathology & Shanxi Key Laboratory of Carcinogenesis and Translational Research on Esophageal Cancer, Shanxi Medical University, Taiyuan, Shanxi 030001 P. R. China.
Zou B; Department of Pathology & Shanxi Key Laboratory of Carcinogenesis and Translational Research on Esophageal Cancer, Shanxi Medical University, Taiyuan, Shanxi 030001 P. R. China.
Liu X; Department of Pathology & Shanxi Key Laboratory of Carcinogenesis and Translational Research on Esophageal Cancer, Shanxi Medical University, Taiyuan, Shanxi 030001 P. R. China.
Cheng Y; College of Letter & Science, University of California Berkeley, Berkeley, California, USA.
Guo S; Department of Tumor Surgery, Shanxi Cancer Hospital, Taiyuan, Shanxi 030001, P.R. China.
Cheng X; Department of Pathology & Shanxi Key Laboratory of Carcinogenesis and Translational Research on Esophageal Cancer, Shanxi Medical University, Taiyuan, Shanxi 030001 P. R. China.
Cui Y; Department of Pathology & Shanxi Key Laboratory of Carcinogenesis and Translational Research on Esophageal Cancer, Shanxi Medical University, Taiyuan, Shanxi 030001 P. R. China.

Theranostics ; 10(4): 1798-1813, 2020.

Article em En | MEDLINE | ID: mdl-32042337

Assuntos

Transição Epitelial-Mesenquimal/genética; Carcinoma de Células Escamosas do Esôfago/genética; Fatores de Transcrição da Família Snail/metabolismo; Fatores de Transcrição/genética; Adulto; Idoso; Caderinas/metabolismo; Linhagem Celular Tumoral/metabolismo; Movimento Celular/genética; Proliferação de Células/genética; Códon sem Sentido; Carcinoma de Células Escamosas do Esôfago/mortalidade; Feminino; Genes Supressores de Tumor/fisiologia; Humanos; Masculino; Pessoa de Meia-Idade; Invasividade Neoplásica; Estadiamento de Neoplasias/métodos; Prognóstico; Análise Serial de Tecidos/métodos; Fatores de Transcrição/metabolismo; Proteínas Supressoras de Tumor; Vimentina/metabolismo

Palavras-chave

ESCC; SNAI1.; ZNF750; epithelial-to-mesenchymal transition; mutation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Transição Epitelial-Mesenquimal / Fatores de Transcrição da Família Snail / Carcinoma de Células Escamosas do Esôfago Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Theranostics Ano de publicação: 2020 Tipo de documento: Article

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