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Precise Targeting of miRNA Sites Restores CFTR Activity in CF Bronchial Epithelial Cells.
De Santi, Chiara; Fernández Fernández, Elena; Gaul, Rachel; Vencken, Sebastian; Glasgow, Arlene; Oglesby, Irene K; Hurley, Killian; Hawkins, Finn; Mitash, Nilay; Mu, Fangping; Raoof, Rana; Henshall, David C; Cutrona, Meritxell B; Simpson, Jeremy C; Harvey, Brian J; Linnane, Barry; McNally, Paul; Cryan, Sally Ann; MacLoughlin, Ronan; Swiatecka-Urban, Agnieszka; Greene, Catherine M.
Afiliação
  • De Santi C; Department of Clinical Microbiology, Royal College of Surgeons in Ireland, Dublin 9, Ireland. Electronic address: chiaradesanti@rcsi.ie.
  • Fernández Fernández E; Department of Clinical Microbiology, Royal College of Surgeons in Ireland, Dublin 9, Ireland.
  • Gaul R; School of Pharmacy and Tissue Engineering Research Group, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
  • Vencken S; Department of Clinical Microbiology, Royal College of Surgeons in Ireland, Dublin 9, Ireland.
  • Glasgow A; Department of Clinical Microbiology, Royal College of Surgeons in Ireland, Dublin 9, Ireland.
  • Oglesby IK; Department of Medicine, Royal College of Surgeons in Ireland, Dublin 9, Ireland.
  • Hurley K; Department of Medicine, Royal College of Surgeons in Ireland, Dublin 9, Ireland.
  • Hawkins F; Center for Regenerative Medicine, Boston University and Boston Medical Center, Boston, MA 02118, USA; The Pulmonary Center and Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA.
  • Mitash N; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
  • Mu F; Center for Research Computing, University of Pittsburgh, Pittsburgh, PA 15213, USA.
  • Raoof R; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
  • Henshall DC; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
  • Cutrona MB; School of Biology and Environmental Science, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland.
  • Simpson JC; School of Biology and Environmental Science, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland.
  • Harvey BJ; Department of Molecular Medicine, Royal College of Surgeons in Ireland, Dublin 9, Ireland.
  • Linnane B; University Hospital Limerick, Dooradoyle, Limerick, Ireland.
  • McNally P; Department of Pediatrics, Royal College of Surgeons in Ireland, Dublin 2, Ireland; National Children's Research Centre, Children's Health Ireland at Crumlin, Dublin 12, Ireland.
  • Cryan SA; School of Pharmacy and Tissue Engineering Research Group, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
  • MacLoughlin R; Aerogen Limited, Galway Business Park, Dangan, Galway, Ireland.
  • Swiatecka-Urban A; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
  • Greene CM; Department of Clinical Microbiology, Royal College of Surgeons in Ireland, Dublin 9, Ireland.
Mol Ther ; 28(4): 1190-1199, 2020 04 08.
Article em En | MEDLINE | ID: mdl-32059764

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oligonucleotídeos / Brônquios / Regulador de Condutância Transmembrana em Fibrose Cística / Fibrose Cística / MicroRNAs Tipo de estudo: Prognostic_studies Limite: Adult / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged Idioma: En Revista: Mol Ther Assunto da revista: BIOLOGIA MOLECULAR / TERAPEUTICA Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oligonucleotídeos / Brônquios / Regulador de Condutância Transmembrana em Fibrose Cística / Fibrose Cística / MicroRNAs Tipo de estudo: Prognostic_studies Limite: Adult / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged Idioma: En Revista: Mol Ther Assunto da revista: BIOLOGIA MOLECULAR / TERAPEUTICA Ano de publicação: 2020 Tipo de documento: Article