C5, A Cassaine Diterpenoid Amine, Induces Apoptosis via the Extrinsic Pathways in Human Lung Cancer Cells and Human Lymphoma Cells.

Kim, Hyo-Jin; Seo, Bo-Gyeong; Kim, Kwang Dong; Yoo, Jiyun; Lee, Joon-Hee; Min, Byung-Sun; Lee, Jeong-Hyung; Hwangbo, Cheol

Kim, Hyo-Jin; Seo, Bo-Gyeong; Kim, Kwang Dong; Yoo, Jiyun; Lee, Joon-Hee; Min, Byung-Sun; Lee, Jeong-Hyung; Hwangbo, Cheol.

Afiliação

Kim HJ; Division of Life Science, College of Natural Sciences, Gyeongsang National University, Jinju 52828, Korea.
Seo BG; Division of Applied Life Science (BK21 Plus), PMBBRC and Research institute of Life Sciences, Geongsang National University, Jinju 52828, Korea.
Kim KD; Division of Life Science, College of Natural Sciences, Gyeongsang National University, Jinju 52828, Korea.
Yoo J; Division of Applied Life Science (BK21 Plus), PMBBRC and Research institute of Life Sciences, Geongsang National University, Jinju 52828, Korea.
Lee JH; Division of Life Science, College of Natural Sciences, Gyeongsang National University, Jinju 52828, Korea.
Min BS; Division of Applied Life Science (BK21 Plus), PMBBRC and Research institute of Life Sciences, Geongsang National University, Jinju 52828, Korea.
Lee JH; Division of Life Science, College of Natural Sciences, Gyeongsang National University, Jinju 52828, Korea.
Hwangbo C; Division of Applied Life Science (BK21 Plus), PMBBRC and Research institute of Life Sciences, Geongsang National University, Jinju 52828, Korea.

Int J Mol Sci ; 21(4)2020 Feb 14.

Article em En | MEDLINE | ID: mdl-32075108

Assuntos

Alcaloides/farmacologia; Apoptose/efeitos dos fármacos; Alcaloides/química; Proteína Reguladora de Apoptosis Semelhante a CASP8 e FADD/genética; Proteína Reguladora de Apoptosis Semelhante a CASP8 e FADD/metabolismo; Caspase 8/metabolismo; Linhagem Celular Tumoral; Sobrevivência Celular/efeitos dos fármacos; Fabaceae/química; Fabaceae/metabolismo; Proteína de Domínio de Morte Associada a Fas/metabolismo; Humanos; Neoplasias Pulmonares/metabolismo; Neoplasias Pulmonares/patologia; Linfoma/metabolismo; Linfoma/patologia; Proteínas Proto-Oncogênicas c-bcl-2/genética; Proteínas Proto-Oncogênicas c-bcl-2/metabolismo

Palavras-chave

Bcl-2; C5 (3ß-Acetyl-nor-erythrophlamide); apoptosis; caspase-8; extrinsic pathways

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Apoptose / Alcaloides Limite: Humans Idioma: En Revista: Int J Mol Sci Ano de publicação: 2020 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google