Activin A Expressed in Rheumatoid Synovial Cells Downregulates TNF&#945;-Induced CXCL10 Expression and Osteoclastogenesis.

Kuranobu, Tatsuomi; Mokuda, Sho; Oi, Katsuhiro; Tokunaga, Tadahiro; Yukawa, Kazutoshi; Kohno, Hiroki; Yoshida, Yusuke; Hirata, Shintaro; Sugiyama, Eiji

Activin A Expressed in Rheumatoid Synovial Cells Downregulates TNFα-Induced CXCL10 Expression and Osteoclastogenesis.

Kuranobu, Tatsuomi; Mokuda, Sho; Oi, Katsuhiro; Tokunaga, Tadahiro; Yukawa, Kazutoshi; Kohno, Hiroki; Yoshida, Yusuke; Hirata, Shintaro; Sugiyama, Eiji.

Afiliação

Kuranobu T; Department of Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima, Japan.
Mokuda S; Department of Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima, Japan.
Oi K; Department of Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima, Japan.
Tokunaga T; Department of Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima, Japan.
Yukawa K; Department of Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima, Japan.
Kohno H; Department of Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima, Japan.
Yoshida Y; Department of Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima, Japan.
Hirata S; Department of Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima, Japan.
Sugiyama E; Department of Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima, Japan, esugiyam@hiroshima-u.ac.jp.

Pathobiology ; 87(3): 198-207, 2020.

Article em En | MEDLINE | ID: mdl-32126552

Assuntos

Ativinas/genética; Quimiocina CXCL10/genética; Cápsula Articular/citologia; Osteogênese; Fator de Necrose Tumoral alfa/genética; Diferenciação Celular; Células Cultivadas; Citocinas/imunologia; Regulação para Baixo; Humanos; Cápsula Articular/imunologia; Leucócitos Mononucleares/imunologia; Fator de Necrose Tumoral alfa/imunologia

Palavras-chave

Activin A; CXCL10; Osteoclastogenesis; Rheumatoid arthritis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteogênese / Fator de Necrose Tumoral alfa / Cápsula Articular / Ativinas / Quimiocina CXCL10 Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Pathobiology Assunto da revista: PATOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Japão

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