Stepwise Promoter Melting by Bacterial RNA Polymerase.

Chen, James; Chiu, Courtney; Gopalkrishnan, Saumya; Chen, Albert Y; Olinares, Paul Dominic B; Saecker, Ruth M; Winkelman, Jared T; Maloney, Michael F; Chait, Brian T; Ross, Wilma; Gourse, Richard L; Campbell, Elizabeth A; Darst, Seth A

Chen, James; Chiu, Courtney; Gopalkrishnan, Saumya; Chen, Albert Y; Olinares, Paul Dominic B; Saecker, Ruth M; Winkelman, Jared T; Maloney, Michael F; Chait, Brian T; Ross, Wilma; Gourse, Richard L; Campbell, Elizabeth A; Darst, Seth A.

Afiliação

Chen J; Laboratory of Molecular Biophysics, The Rockefeller University, New York, NY 10065, USA.
Chiu C; Laboratory of Molecular Biophysics, The Rockefeller University, New York, NY 10065, USA.
Gopalkrishnan S; Department of Bacteriology, University of Wisconsin-Madison, Madison, WI 53706, USA.
Chen AY; Department of Bacteriology, University of Wisconsin-Madison, Madison, WI 53706, USA.
Olinares PDB; Laboratory of Mass Spectrometry and Gaseous Ion Chemistry, The Rockefeller University, New York, NY 10065, USA.
Saecker RM; Laboratory of Molecular Biophysics, The Rockefeller University, New York, NY 10065, USA.
Winkelman JT; Department of Bacteriology, University of Wisconsin-Madison, Madison, WI 53706, USA.
Maloney MF; Department of Bacteriology, University of Wisconsin-Madison, Madison, WI 53706, USA.
Chait BT; Laboratory of Mass Spectrometry and Gaseous Ion Chemistry, The Rockefeller University, New York, NY 10065, USA.
Ross W; Department of Bacteriology, University of Wisconsin-Madison, Madison, WI 53706, USA.
Gourse RL; Department of Bacteriology, University of Wisconsin-Madison, Madison, WI 53706, USA.
Campbell EA; Laboratory of Molecular Biophysics, The Rockefeller University, New York, NY 10065, USA.
Darst SA; Laboratory of Molecular Biophysics, The Rockefeller University, New York, NY 10065, USA. Electronic address: darst@rockefeller.edu.

Mol Cell ; 78(2): 275-288.e6, 2020 04 16.

Article em En | MEDLINE | ID: mdl-32160514

Assuntos

RNA Polimerases Dirigidas por DNA/genética; Regiões Promotoras Genéticas/genética; RNA Bacteriano/genética; Iniciação da Transcrição Genética; Microscopia Crioeletrônica; RNA Polimerases Dirigidas por DNA/química; Escherichia coli/genética; Conformação de Ácido Nucleico; Ligação Proteica/genética; Conformação Proteica

Palavras-chave

Conformational change; Cryoelectron microscopy; DNA; Open promoter complex formation; Promoter DNA; RNA polymerase; TraR; Transcription initiation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA Polimerases Dirigidas por DNA / RNA Bacteriano / Regiões Promotoras Genéticas / Iniciação da Transcrição Genética Idioma: En Revista: Mol Cell Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

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