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The HDAC and PI3K dual inhibitor CUDC-907 synergistically enhances the antileukemic activity of venetoclax in preclinical models of acute myeloid leukemia.
Li, Xinyu; Su, Yongwei; Hege, Katie; Madlambayan, Gerard; Edwards, Holly; Knight, Tristan; Polin, Lisa; Kushner, Juiwanna; Dzinic, Sijana H; White, Kathryn; Yang, Jay; Miller, Regan; Wang, Guan; Zhao, Lijing; Wang, Yue; Lin, Hai; Taub, Jeffrey W; Ge, Yubin.
Afiliação
  • Li X; School of Life Sciences, Jilin University, Changchun, China.
  • Su Y; School of Life Sciences, Jilin University, Changchun, China.
  • Hege K; Cancer Biology Graduate Program, Wayne State University School of Medicine, Detroit, MI, USA.
  • Madlambayan G; Department of Biological Sciences, Oakland University, Rochester, MI, USA.
  • Edwards H; Wayne State University, Barbara Ann Karmanos Cancer Institute, Detroit, MI, USA.
  • Knight T; Dept of Pediatrics, Children's Hospital of Michigan, Wayne State University, Detroit, MI, USA.
  • Polin L; Wayne State University, Barbara Ann Karmanos Cancer Institute, Detroit, MI, USA.
  • Kushner J; Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA.
  • Dzinic SH; Wayne State University, Barbara Ann Karmanos Cancer Institute, Detroit, MI, USA.
  • White K; Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA.
  • Yang J; Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA.
  • Miller R; Department of Biological Sciences, Oakland University, Rochester, MI, USA.
  • Wang G; School of Life Sciences, Jilin University, Changchun, China.
  • Zhao L; Department of Rehabilitation, School of Nursing, Jilin University, Changchun, China.
  • Wang Y; Dept. of Pediatric Hematology and Oncology, First Hospital of Jilin University, Changchun, China.
  • Lin H; Dept. of Hematology and Oncology, The First Hospital of Jilin University, Changchun, China.
  • Taub JW; Dept of Pediatrics, Children Hospital of Michigan, Wayne State University, Detroit, MI, USA.
  • Ge Y; Wayne State University School of Medicine, Detroit, MI, USA.
Haematologica ; 106(5): 1262-1277, 2021 05 01.
Article em En | MEDLINE | ID: mdl-32165486

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Fosfatidilinositol 3-Quinases Limite: Animals / Humans Idioma: En Revista: Haematologica Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Fosfatidilinositol 3-Quinases Limite: Animals / Humans Idioma: En Revista: Haematologica Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China