The chemokine CCL7 regulates invadopodia maturation and MMP-9 mediated collagen degradation in liver-metastatic carcinoma cells.

Qi, Shu; Perrino, Stephanie; Miao, Xinyu; Lamarche-Vane, Nathalie; Brodt, Pnina

Qi, Shu; Perrino, Stephanie; Miao, Xinyu; Lamarche-Vane, Nathalie; Brodt, Pnina.

Afiliação

Qi S; Department of Surgery, Research Institute of the McGill University Health Centre, 1001 Décarie Blvd, Glen Site, Room E.02.6230, Montréal, QC, H4A 3J1, Canada; Department of the Cancer Research Program, Research Institute of the McGill University Health Centre 1001 Décarie Blvd, Glen Site, Room E.02.
Perrino S; Department of Surgery, Research Institute of the McGill University Health Centre, 1001 Décarie Blvd, Glen Site, Room E.02.6230, Montréal, QC, H4A 3J1, Canada; Department of the Cancer Research Program, Research Institute of the McGill University Health Centre 1001 Décarie Blvd, Glen Site, Room E.02.
Miao X; Departments of Anatomy and Cell Biology, Research Institute of the McGill University Health Centre 1001 Décarie Blvd, Glen Site, Room E.02.6230, Montréal, QC, H4A 3J1, Canada; Department of McGill University, Research Institute of the McGill University Health Centre 1001 Décarie Blvd, Glen Site, Roo
Lamarche-Vane N; Departments of Anatomy and Cell Biology, Research Institute of the McGill University Health Centre 1001 Décarie Blvd, Glen Site, Room E.02.6230, Montréal, QC, H4A 3J1, Canada; Department of McGill University, Research Institute of the McGill University Health Centre 1001 Décarie Blvd, Glen Site, Roo
Brodt P; Department of Surgery, Research Institute of the McGill University Health Centre, 1001 Décarie Blvd, Glen Site, Room E.02.6230, Montréal, QC, H4A 3J1, Canada; Department of Medicine, Research Institute of the McGill University Health Centre, 1001 Décarie Blvd, Glen Site, Room E.02.6230, Montréal, QC

Cancer Lett ; 483: 98-113, 2020 07 28.

Article em En | MEDLINE | ID: mdl-32217106

Assuntos

Carcinoma Pulmonar de Lewis/enzimologia; Movimento Celular; Quimiocina CCL7/metabolismo; Colágeno/metabolismo; Neoplasias do Colo/enzimologia; Neoplasias Hepáticas/enzimologia; Metaloproteinase 9 da Matriz/metabolismo; Podossomos/enzimologia; Animais; Carcinoma Pulmonar de Lewis/genética; Carcinoma Pulmonar de Lewis/patologia; Quimiocina CCL7/genética; Neoplasias do Colo/genética; Neoplasias do Colo/patologia; MAP Quinases Reguladas por Sinal Extracelular/metabolismo; Humanos; Neoplasias Hepáticas/genética; Neoplasias Hepáticas/secundário; Metaloproteinase 9 da Matriz/genética; Camundongos; Fosfatidilinositol 3-Quinase/metabolismo; Podossomos/genética; Podossomos/patologia; Transporte Proteico; Proteólise; Receptores CCR3/genética; Receptores CCR3/metabolismo; Proteína rhoA de Ligação ao GTP/genética; Proteína rhoA de Ligação ao GTP/metabolismo

Palavras-chave

CCL7; Chemokines; Colon cancer; Extracellular matrix; Invadopodia; Liver metastasis; Lung cancer; MMP-9

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Movimento Celular / Colágeno / Neoplasias do Colo / Carcinoma Pulmonar de Lewis / Metaloproteinase 9 da Matriz / Quimiocina CCL7 / Podossomos / Neoplasias Hepáticas Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Cancer Lett Ano de publicação: 2020 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google