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Acetylene containing cyclo(L-Tyr-L-Tyr)-analogs as mechanism-based inhibitors of CYP121A1 from Mycobacterium tuberculosis.
Ortega Ugalde, Sandra; Wallraven, Kerstin; Speer, Alexander; Bitter, Wilbert; Grossmann, Tom N; Commandeur, Jan N M.
Afiliação
  • Ortega Ugalde S; Division of Molecular and Computational Toxicology, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Faculty of Sciences, Vrije Universiteit, Amsterdam, The Netherlands.
  • Wallraven K; Department of Chemistry and Pharmaceutical Sciences, Faculty of Sciences, Vrije Universiteit, Amsterdam, The Netherlands.
  • Speer A; Department of Medical Microbiology and Infection Control, Amsterdam UMC, Amsterdam, The Netherlands.
  • Bitter W; Department of Medical Microbiology and Infection Control, Amsterdam UMC, Amsterdam, The Netherlands.
  • Grossmann TN; Department of Chemistry and Pharmaceutical Sciences, Faculty of Sciences, Vrije Universiteit, Amsterdam, The Netherlands. Electronic address: t.n.grossmann@vu.nl.
  • Commandeur JNM; Division of Molecular and Computational Toxicology, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Faculty of Sciences, Vrije Universiteit, Amsterdam, The Netherlands. Electronic address: j.n.m.commandeur@vu.nl.
Biochem Pharmacol ; 177: 113938, 2020 07.
Article em En | MEDLINE | ID: mdl-32224137
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos Cíclicos / Acetileno / Tirosina / Desenho de Fármacos / Sistema Enzimático do Citocromo P-450 / Inibidores das Enzimas do Citocromo P-450 / Mycobacterium tuberculosis / Antituberculosos Idioma: En Revista: Biochem Pharmacol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Holanda
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos Cíclicos / Acetileno / Tirosina / Desenho de Fármacos / Sistema Enzimático do Citocromo P-450 / Inibidores das Enzimas do Citocromo P-450 / Mycobacterium tuberculosis / Antituberculosos Idioma: En Revista: Biochem Pharmacol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Holanda