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Oncogenic KrasG12D causes myeloproliferation via NLRP3 inflammasome activation.
Hamarsheh, Shaima'a; Osswald, Lena; Saller, Benedikt S; Unger, Susanne; De Feo, Donatella; Vinnakota, Janaki Manoja; Konantz, Martina; Uhl, Franziska M; Becker, Heiko; Lübbert, Michael; Shoumariyeh, Khalid; Schürch, Christoph; Andrieux, Geoffroy; Venhoff, Nils; Schmitt-Graeff, Annette; Duquesne, Sandra; Pfeifer, Dietmar; Cooper, Matthew A; Lengerke, Claudia; Boerries, Melanie; Duyster, Justus; Niemeyer, Charlotte M; Erlacher, Miriam; Blazar, Bruce R; Becher, Burkard; Groß, Olaf; Brummer, Tilman; Zeiser, Robert.
Afiliação
  • Hamarsheh S; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Osswald L; Faculty of Biology, University of Freiburg, Freiburg, Germany.
  • Saller BS; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Unger S; Faculty of Biology, University of Freiburg, Freiburg, Germany.
  • De Feo D; Institute of Neuropathology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Vinnakota JM; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.
  • Konantz M; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.
  • Uhl FM; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Becker H; Faculty of Biology, University of Freiburg, Freiburg, Germany.
  • Lübbert M; Department of Biomedicine, University of Basel and University Hospital Basel, Basel, Switzerland.
  • Shoumariyeh K; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Schürch C; Faculty of Biology, University of Freiburg, Freiburg, Germany.
  • Andrieux G; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Venhoff N; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Schmitt-Graeff A; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Duquesne S; Department of Biomedicine, University of Basel and University Hospital Basel, Basel, Switzerland.
  • Pfeifer D; Institute of Medical Bioinformatics and Systems Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Cooper MA; Clinic for Rheumatology and Clinical Immunology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Lengerke C; University of Freiburg, Freiburg, Germany.
  • Boerries M; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Duyster J; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Niemeyer CM; Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia.
  • Erlacher M; Department of Biomedicine, University of Basel and University Hospital Basel, Basel, Switzerland.
  • Blazar BR; Institute of Medical Bioinformatics and Systems Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Becher B; German Cancer Consortium (DKTK) Partner Site Freiburg, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Groß O; Comprehensive Cancer Centre Freiburg (CCCF), University of Freiburg, Freiburg, Germany.
  • Brummer T; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Zeiser R; German Cancer Consortium (DKTK) Partner Site Freiburg, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Nat Commun ; 11(1): 1659, 2020 04 03.
Article em En | MEDLINE | ID: mdl-32246016
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas p21(ras) / Inflamassomos / Proteína 3 que Contém Domínio de Pirina da Família NLR / Transtornos Mieloproliferativos Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas p21(ras) / Inflamassomos / Proteína 3 que Contém Domínio de Pirina da Família NLR / Transtornos Mieloproliferativos Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha