A hallmark of phospholamban functional divergence is located in the N-terminal phosphorylation domain.

Fernández-de Gortari, Eli; Aguayo-Ortiz, Rodrigo; Autry, Joseph M; Michel Espinoza-Fonseca, L

Fernández-de Gortari, Eli; Aguayo-Ortiz, Rodrigo; Autry, Joseph M; Michel Espinoza-Fonseca, L.

Afiliação

Fernández-de Gortari E; Center for Arrhythmia Research, Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI 48109, USA.
Aguayo-Ortiz R; Center for Arrhythmia Research, Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI 48109, USA.
Autry JM; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA.
Michel Espinoza-Fonseca L; Biophysical Technology Center, University of Minnesota, Minneapolis, MN 55455, USA.

Comput Struct Biotechnol J ; 18: 705-713, 2020.

Article em En | MEDLINE | ID: mdl-32257054

Palavras-chave

Calcium pump; Functional divergence; M4S4, cytosolic extension of transmembrane helix M4; Molecular dynamics simulations; PLB, phospholamban; POPC, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine; Phospholamban; Phosphorylation domain; RMSD, root mean square deviation; SERCA, sarcoplasmic reticulum Ca2+-ATPase; SLN, sarcolipin; Sarcolipin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Comput Struct Biotechnol J Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

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