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The mitochondria-targeted peptide SS-31 binds lipid bilayers and modulates surface electrostatics as a key component of its mechanism of action.
Mitchell, Wayne; Ng, Emily A; Tamucci, Jeffrey D; Boyd, Kevin J; Sathappa, Murugappan; Coscia, Adrian; Pan, Meixia; Han, Xianlin; Eddy, Nicholas A; May, Eric R; Szeto, Hazel H; Alder, Nathan N.
Afiliação
  • Mitchell W; Department of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut 06269.
  • Ng EA; Department of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut 06269.
  • Tamucci JD; Department of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut 06269.
  • Boyd KJ; Department of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut 06269.
  • Sathappa M; Department of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut 06269.
  • Coscia A; Department of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut 06269.
  • Pan M; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229.
  • Han X; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229; Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229.
  • Eddy NA; Institute of Materials Science, University of Connecticut, Storrs, Connecticut 06269.
  • May ER; Department of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut 06269.
  • Szeto HH; Social Profit Network Research Lab, Alexandria LaunchLabs, New York, New York 10016.
  • Alder NN; Department of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut 06269. Electronic address: nathan.alder@uconn.edu.
J Biol Chem ; 295(21): 7452-7469, 2020 05 22.
Article em En | MEDLINE | ID: mdl-32273339
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oligopeptídeos / Bicamadas Lipídicas Tipo de estudo: Prognostic_studies Idioma: En Revista: J Biol Chem Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oligopeptídeos / Bicamadas Lipídicas Tipo de estudo: Prognostic_studies Idioma: En Revista: J Biol Chem Ano de publicação: 2020 Tipo de documento: Article