The interferon-inducible protein TDRD7 inhibits AMP-activated protein kinase and thereby restricts autophagy-independent virus replication.

Subramanian, Gayatri; Popli, Sonam; Chakravarty, Sukanya; Taylor, R Travis; Chakravarti, Ritu; Chattopadhyay, Saurabh

Subramanian, Gayatri; Popli, Sonam; Chakravarty, Sukanya; Taylor, R Travis; Chakravarti, Ritu; Chattopadhyay, Saurabh.

Afiliação

Subramanian G; Department of Medical Microbiology and Immunology, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio 43614.
Popli S; Department of Medical Microbiology and Immunology, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio 43614.
Chakravarty S; Department of Medical Microbiology and Immunology, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio 43614.
Taylor RT; Department of Medical Microbiology and Immunology, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio 43614.
Chakravarti R; Department of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio 43614.
Chattopadhyay S; Department of Medical Microbiology and Immunology, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio 43614 Saurabh.Chattopadhyay@UToledo.edu.

J Biol Chem ; 295(20): 6811-6822, 2020 05 15.

Article em En | MEDLINE | ID: mdl-32273341

Assuntos

Proteínas Quinases Ativadas por AMP/metabolismo; Autofagia; Herpesvirus Humano 1/fisiologia; Ribonucleoproteínas/metabolismo; Replicação Viral; Proteínas Quinases Ativadas por AMP/genética; Animais; Chlorocebus aethiops; Células HeLa; Humanos; Camundongos; Ribonucleoproteínas/genética; Células Vero

Palavras-chave

AMP-activated kinase (AMPK); TDRD7; autophagy; herpesvirus; innate immunity; interferon; interferon-stimulated genes

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ribonucleoproteínas / Autofagia / Replicação Viral / Herpesvirus Humano 1 / Proteínas Quinases Ativadas por AMP Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2020 Tipo de documento: Article

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