An immunoinformatic approach driven by experimental proteomics: in silico design of a subunit candidate vaccine targeting secretory proteins of Leishmania donovani amastigotes.

Khan, Md Anik Ashfaq; Ami, Jenifar Quaiyum; Faisal, Khaledul; Chowdhury, Rajashree; Ghosh, Prakash; Hossain, Faria; Abd El Wahed, Ahmed; Mondal, Dinesh

Khan, Md Anik Ashfaq; Ami, Jenifar Quaiyum; Faisal, Khaledul; Chowdhury, Rajashree; Ghosh, Prakash; Hossain, Faria; Abd El Wahed, Ahmed; Mondal, Dinesh.

Afiliação

Khan MAA; Nutrition and Clinical Services Division, International Centre for Diarrheal Disease Research, Bangladesh, Dhaka, 1212, Bangladesh.
Ami JQ; Infectious Diseases Division, International Centre for Diarrheal Disease Research, Bangladesh, Dhaka, 1212, Bangladesh.
Faisal K; Nutrition and Clinical Services Division, International Centre for Diarrheal Disease Research, Bangladesh, Dhaka, 1212, Bangladesh.
Chowdhury R; Nutrition and Clinical Services Division, International Centre for Diarrheal Disease Research, Bangladesh, Dhaka, 1212, Bangladesh.
Ghosh P; Nutrition and Clinical Services Division, International Centre for Diarrheal Disease Research, Bangladesh, Dhaka, 1212, Bangladesh.
Hossain F; Nutrition and Clinical Services Division, International Centre for Diarrheal Disease Research, Bangladesh, Dhaka, 1212, Bangladesh.
Abd El Wahed A; Microbiology and Animal Hygiene Division, Georg-August-University Goettingen, Burckhardtweg 2, 37077, Göttingen, Germany. abdelwahed@gwdg.de.
Mondal D; Nutrition and Clinical Services Division, International Centre for Diarrheal Disease Research, Bangladesh, Dhaka, 1212, Bangladesh. din63d@icddrb.org.

Parasit Vectors ; 13(1): 196, 2020 Apr 15.

Article em En | MEDLINE | ID: mdl-32295617

Assuntos

Antígenos de Protozoários/imunologia; Epitopos de Linfócito T/imunologia; Leishmania donovani/imunologia; Vacinas contra Leishmaniose/imunologia; Adjuvantes Imunológicos/química; Linfócitos T CD4-Positivos/imunologia; Linfócitos T CD8-Positivos/imunologia; Biologia Computacional; Leishmania infantum/imunologia; Leishmaniose Visceral/parasitologia; Simulação de Acoplamento Molecular; Simulação de Dinâmica Molecular; Proteômica; Proteínas de Protozoários/imunologia; Vacinas de Subunidades Antigênicas/imunologia

Palavras-chave

In silico vaccine design; Reverse vaccinology using proteomics; Visceral leishmaniasis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leishmania donovani / Epitopos de Linfócito T / Vacinas contra Leishmaniose / Antígenos de Protozoários Tipo de estudo: Prognostic_studies Idioma: En Revista: Parasit Vectors Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Bangladesh

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