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Heterochromatin-Driven Nuclear Softening Protects the Genome against Mechanical Stress-Induced Damage.
Nava, Michele M; Miroshnikova, Yekaterina A; Biggs, Leah C; Whitefield, Daniel B; Metge, Franziska; Boucas, Jorge; Vihinen, Helena; Jokitalo, Eija; Li, Xinping; García Arcos, Juan Manuel; Hoffmann, Bernd; Merkel, Rudolf; Niessen, Carien M; Dahl, Kris Noel; Wickström, Sara A.
Afiliação
  • Nava MM; Helsinki Institute of Life Science, Biomedicum Helsinki, University of Helsinki, 00290 Helsinki, Finland; Wihuri Research Institute, Biomedicum Helsinki, University of Helsinki, 00290 Helsinki, Finland; Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki, 00290 He
  • Miroshnikova YA; Helsinki Institute of Life Science, Biomedicum Helsinki, University of Helsinki, 00290 Helsinki, Finland; Wihuri Research Institute, Biomedicum Helsinki, University of Helsinki, 00290 Helsinki, Finland; Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki, 00290 He
  • Biggs LC; Helsinki Institute of Life Science, Biomedicum Helsinki, University of Helsinki, 00290 Helsinki, Finland; Wihuri Research Institute, Biomedicum Helsinki, University of Helsinki, 00290 Helsinki, Finland; Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki, 00290 He
  • Whitefield DB; Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, USA.
  • Metge F; Max Planck Institute for Biology of Ageing, 50931 Cologne, Germany.
  • Boucas J; Max Planck Institute for Biology of Ageing, 50931 Cologne, Germany.
  • Vihinen H; Electron Microscopy Unit, Institute of Biotechnology, HiLIFE, University of Helsinki, 00014 Helsinki, Finland.
  • Jokitalo E; Electron Microscopy Unit, Institute of Biotechnology, HiLIFE, University of Helsinki, 00014 Helsinki, Finland.
  • Li X; Max Planck Institute for Biology of Ageing, 50931 Cologne, Germany.
  • García Arcos JM; Institut Curie, PSL Research University, CNRS, UMR 144 and Institut Pierre-Gilles de Gennes, PSL Research University, 75005 Paris, France.
  • Hoffmann B; Forschungszentrum Jülich, Institute of Biological Information Processing-2: Mechanobiology, 52428 Jülich, Germany.
  • Merkel R; Forschungszentrum Jülich, Institute of Biological Information Processing-2: Mechanobiology, 52428 Jülich, Germany.
  • Niessen CM; Cologne Excellence Cluster for Stress Responses in Ageing-Associated Diseases (CECAD), University of Cologne, 50931 Cologne, Germany; Department of Dermatology, Center for Molecular Medicine, University of Cologne, 50931 Cologne, Germany.
  • Dahl KN; Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, USA; Department of Chemical Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, USA.
  • Wickström SA; Helsinki Institute of Life Science, Biomedicum Helsinki, University of Helsinki, 00290 Helsinki, Finland; Wihuri Research Institute, Biomedicum Helsinki, University of Helsinki, 00290 Helsinki, Finland; Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki, 00290 He
Cell ; 181(4): 800-817.e22, 2020 05 14.
Article em En | MEDLINE | ID: mdl-32302590
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Heterocromatina / Núcleo Celular / Mecanotransdução Celular Limite: Animals / Humans / Male Idioma: En Revista: Cell Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Heterocromatina / Núcleo Celular / Mecanotransdução Celular Limite: Animals / Humans / Male Idioma: En Revista: Cell Ano de publicação: 2020 Tipo de documento: Article