Inhibition of DNA methylation in proliferating human lymphoma cells by immune cell oxidants.

O'Connor, Karina M; Das, Andrew B; Winterbourn, Christine C; Hampton, Mark B

O'Connor, Karina M; Das, Andrew B; Winterbourn, Christine C; Hampton, Mark B.

Afiliação

O'Connor KM; Centre for Free Radical Research, Department of Pathology and Biomedical Science, University of Otago, Christchurch, New Zealand.
Das AB; Centre for Free Radical Research, Department of Pathology and Biomedical Science, University of Otago, Christchurch, New Zealand.
Winterbourn CC; Centre for Free Radical Research, Department of Pathology and Biomedical Science, University of Otago, Christchurch, New Zealand.
Hampton MB; Centre for Free Radical Research, Department of Pathology and Biomedical Science, University of Otago, Christchurch, New Zealand mark.hampton@otago.ac.nz.

J Biol Chem ; 295(23): 7839-7848, 2020 06 05.

Article em En | MEDLINE | ID: mdl-32312750

Assuntos

Cloraminas/farmacologia; Metilação de DNA/efeitos dos fármacos; DNA de Neoplasias/efeitos dos fármacos; Glicina/análogos & derivados; Linfoma/tratamento farmacológico; Linfoma/patologia; Oxidantes/farmacologia; Proliferação de Células/efeitos dos fármacos; Sobrevivência Celular/efeitos dos fármacos; Células Cultivadas; DNA de Neoplasias/genética; DNA de Neoplasias/metabolismo; Glicina/farmacologia; Humanos; Células Jurkat; Linfoma/imunologia

Palavras-chave

DNA methylation; DNA methyltransferase (DNMT); epigenetics; glycine chloramine; hydrogen peroxide; inflammation; neutrophil; oxidative stress; redox signaling; tumor microenvironment

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA de Neoplasias / Cloraminas / Oxidantes / Metilação de DNA / Glicina / Linfoma Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Nova Zelândia

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