Rescue of Function of Mutant Luteinising Hormone Receptors with Deficiencies in Cell Surface Expression, Hormone Binding, and Hormone Signalling.

Newton, Claire Louise; Anderson, Ross Calley; Kreuchwig, Annika; Krause, Gerd; Katz, Arieh Anthony; Millar, Robert Peter

Newton, Claire Louise; Anderson, Ross Calley; Kreuchwig, Annika; Krause, Gerd; Katz, Arieh Anthony; Millar, Robert Peter.

Afiliação

Newton CL; Centre for Neuroendocrinology, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa, claire.newton@up.ac.za.
Anderson RC; Department of Immunology, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa, claire.newton@up.ac.za.
Kreuchwig A; Deanery of Biomedical Sciences, University of Edinburgh, Edinburgh, United Kingdom, claire.newton@up.ac.za.
Krause G; Centre for Neuroendocrinology, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.
Katz AA; Department of Physiology, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.
Millar RP; Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany.

Neuroendocrinology ; 111(5): 451-464, 2021.

Article em En | MEDLINE | ID: mdl-32316022

Assuntos

Regulação Alostérica; Chaperonas Moleculares; Receptores do LH/agonistas; Células HEK293; Humanos; Proteínas Mutantes; Mutação; Dobramento de Proteína

Palavras-chave

Allosteric agonist; G protein-coupled receptor mutations; Luteinising hormone receptors; Pharmacological chaperones; Pharmacoperones; Reproductive dysfunction

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores do LH / Chaperonas Moleculares / Regulação Alostérica Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Neuroendocrinology Ano de publicação: 2021 Tipo de documento: Article

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