Efficacy and safety of clopidogrel versus prasugrel and ticagrelor for coronary artery disease treatment in patients with CYP2C19 LoF alleles: a systemic review and meta-analysis.

Yoon, Ha Young; Lee, Nari; Seong, Jong-Mi; Gwak, Hye Sun

Yoon, Ha Young; Lee, Nari; Seong, Jong-Mi; Gwak, Hye Sun.

Afiliação

Yoon HY; College of Pharmacy and Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 03760, Republic of Korea.
Lee N; College of Pharmacy and Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 03760, Republic of Korea.
Seong JM; College of Pharmacy and Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 03760, Republic of Korea.
Gwak HS; College of Pharmacy and Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 03760, Republic of Korea.

Br J Clin Pharmacol ; 86(8): 1489-1498, 2020 08.

Article em En | MEDLINE | ID: mdl-32320492

Assuntos

Síndrome Coronariana Aguda; Doença da Artéria Coronariana; Alelos; Clopidogrel/efeitos adversos; Citocromo P-450 CYP2C19/genética; Humanos; Inibidores da Agregação Plaquetária/efeitos adversos; Cloridrato de Prasugrel/efeitos adversos; Antagonistas do Receptor Purinérgico P2Y/efeitos adversos; Ticagrelor/efeitos adversos; Resultado do Tratamento

Palavras-chave

CYP2C19 reduced-metabolizers; P2Y12 receptor inhibitors; bleeding; major adverse cardiovascular events; meta-analysis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença da Artéria Coronariana / Síndrome Coronariana Aguda Tipo de estudo: Clinical_trials / Etiology_studies / Observational_studies / Risk_factors_studies / Systematic_reviews Limite: Humans Idioma: En Revista: Br J Clin Pharmacol Ano de publicação: 2020 Tipo de documento: Article

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