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Compound LM9, a novel MyD88 inhibitor, efficiently mitigates inflammatory responses and fibrosis in obesity-induced cardiomyopathy.
Zheng, Xu-Yong; Sun, Chu-Chu; Liu, Qian; Lu, Xiao-Yao; Fu, Li-Li; Liang, Guang; Zhang, Xiu-Hua; Chen, Gao-Zhi.
Afiliação
  • Zheng XY; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China.
  • Sun CC; Department of Pharmacy, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325035, China.
  • Liu Q; The Third Affiliated Hospital of Wenzhou Medical University, Ruian, 325200, China.
  • Lu XY; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China.
  • Fu LL; Department of Pharmacy, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325035, China.
  • Liang G; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China.
  • Zhang XH; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China.
  • Chen GZ; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China.
Acta Pharmacol Sin ; 41(8): 1093-1101, 2020 Aug.
Article em En | MEDLINE | ID: mdl-32341464
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piperazinas / Tiazóis / Fibrose / Fator 88 de Diferenciação Mieloide / Inflamação / Anti-Inflamatórios / Cardiomiopatias Limite: Animals / Humans / Male Idioma: En Revista: Acta Pharmacol Sin Assunto da revista: FARMACOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piperazinas / Tiazóis / Fibrose / Fator 88 de Diferenciação Mieloide / Inflamação / Anti-Inflamatórios / Cardiomiopatias Limite: Animals / Humans / Male Idioma: En Revista: Acta Pharmacol Sin Assunto da revista: FARMACOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China