NEAT1 knockdown suppresses endothelial cell proliferation and induces apoptosis by regulating miR­638/AKT/mTOR signaling in atherosclerosis.

Zhang, Xia; Guan, Ming-Xiu; Jiang, Qiu-Hong; Li, Sai; Zhang, Hong-Yu; Wu, Zhi-Guo; Cong, Hong-Liang; Qi, Xiu-Hui

NEAT1 knockdown suppresses endothelial cell proliferation and induces apoptosis by regulating miR638/AKT/mTOR signaling in atherosclerosis.

Zhang, Xia; Guan, Ming-Xiu; Jiang, Qiu-Hong; Li, Sai; Zhang, Hong-Yu; Wu, Zhi-Guo; Cong, Hong-Liang; Qi, Xiu-Hui.

Afiliação

Zhang X; Department of Cardiology, Tianjin Baodi Hospital, Baodi Clinical College of Tianjin Medical University, Tianjin 301800, P.R. China.
Guan MX; Department of Clinical Laboratory, Tianjin Baodi Hospital, Baodi Clinical College of Tianjin Medical University, Tianjin 301800, P.R. China.
Jiang QH; Department of Cardiology, Tianjin Baodi Hospital, Baodi Clinical College of Tianjin Medical University, Tianjin 301800, P.R. China.
Li S; Department of Cardiology, Shenyang Fourth People's Hospital, Shenyang, Liaoning 110031, P.R. China.
Zhang HY; Department of Cardiology, Tianjin Baodi Hospital, Baodi Clinical College of Tianjin Medical University, Tianjin 301800, P.R. China.
Wu ZG; Department of Cardiology, Tianjin Baodi Hospital, Baodi Clinical College of Tianjin Medical University, Tianjin 301800, P.R. China.
Cong HL; Department of Cardiovascular Medicine, Tianjin Chest Hospital, Tianjin 300202, P.R. China.
Qi XH; Department of Nursing, Tianjin Baodi Hospital, Baodi Clinical College of Tianjin Medical University, Tianjin 301800, P.R. China.

Oncol Rep ; 44(1): 115-125, 2020 07.

Article em En | MEDLINE | ID: mdl-32377692

Assuntos

Aterosclerose/genética; Células Endoteliais/citologia; MicroRNAs/genética; RNA Longo não Codificante/genética; Aterosclerose/metabolismo; Linhagem Celular; Proliferação de Células; Sobrevivência Celular; Células Endoteliais/química; Células Endoteliais/efeitos dos fármacos; Feminino; Técnicas de Silenciamento de Genes; Humanos; Lipoproteínas LDL/efeitos adversos; Masculino; Proteínas Proto-Oncogênicas c-akt/metabolismo; Transdução de Sinais; Serina-Treonina Quinases TOR/metabolismo

Palavras-chave

long non-coding RNA; nuclear paraspeckle assembly transcript 1; atherosclerosis; miR-638; phosphoglycerate kinase 1

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: MicroRNAs / Células Endoteliais / Aterosclerose / RNA Longo não Codificante Limite: Female / Humans / Male Idioma: En Revista: Oncol Rep Assunto da revista: NEOPLASIAS Ano de publicação: 2020 Tipo de documento: Article

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