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Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice.
Alexopoulos, Stephanie J; Chen, Sing-Young; Brandon, Amanda E; Salamoun, Joseph M; Byrne, Frances L; Garcia, Christopher J; Beretta, Martina; Olzomer, Ellen M; Shah, Divya P; Philp, Ashleigh M; Hargett, Stefan R; Lawrence, Robert T; Lee, Brendan; Sligar, James; Carrive, Pascal; Tucker, Simon P; Philp, Andrew; Lackner, Carolin; Turner, Nigel; Cooney, Gregory J; Santos, Webster L; Hoehn, Kyle L.
Afiliação
  • Alexopoulos SJ; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW, 2052, Australia.
  • Chen SY; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW, 2052, Australia.
  • Brandon AE; Sydney Medical School, Charles Perkins Centre, University of Sydney, Sydney, NSW, 2006, Australia.
  • Salamoun JM; Department of Chemistry and Virginia Tech Centre for Drug Discovery, Virginia Tech, Blacksburg, VA, 24061, USA.
  • Byrne FL; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW, 2052, Australia.
  • Garcia CJ; Department of Chemistry and Virginia Tech Centre for Drug Discovery, Virginia Tech, Blacksburg, VA, 24061, USA.
  • Beretta M; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW, 2052, Australia.
  • Olzomer EM; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW, 2052, Australia.
  • Shah DP; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW, 2052, Australia.
  • Philp AM; Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.
  • Hargett SR; Department of Pharmacology, University of Virginia, Charlottesville, VA, 22908, USA.
  • Lawrence RT; Department of Pharmacology, University of Virginia, Charlottesville, VA, 22908, USA.
  • Lee B; Biological Resources Imaging Laboratory, University of New South Wales, Sydney, NSW, 2052, Australia.
  • Sligar J; Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.
  • Carrive P; Department of Anatomy, School of Medical Sciences, University of New South Wales, Sydney, NSW, 2052, Australia.
  • Tucker SP; Continuum Biosciences Pty Ltd., Sydney, NSW, 2035, Australia.
  • Philp A; Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.
  • Lackner C; Institute of Pathology, Medical University of Graz, Graz, Austria.
  • Turner N; Department of Pharmacology, School of Medical Science, University of New South Wales, Sydney, NSW, 2052, Australia.
  • Cooney GJ; Sydney Medical School, Charles Perkins Centre, University of Sydney, Sydney, NSW, 2006, Australia.
  • Santos WL; Department of Chemistry and Virginia Tech Centre for Drug Discovery, Virginia Tech, Blacksburg, VA, 24061, USA. santosw@vt.edu.
  • Hoehn KL; Continuum Biosciences Pty Ltd., Sydney, NSW, 2035, Australia. santosw@vt.edu.
Nat Commun ; 11(1): 2397, 2020 05 14.
Article em En | MEDLINE | ID: mdl-32409697
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxidiazóis / Pirazinas / Resistência à Insulina / Diaminas / Mitocôndrias / Obesidade Limite: Animals / Humans / Male Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Austrália
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxidiazóis / Pirazinas / Resistência à Insulina / Diaminas / Mitocôndrias / Obesidade Limite: Animals / Humans / Male Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Austrália