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Amiodarone disrupts cholesterol biosynthesis pathway and causes accumulation of circulating desmosterol by inhibiting 24-dehydrocholesterol reductase.
Simonen, P; Li, S; Chua, N K; Lampi, A-M; Piironen, V; Lommi, J; Sinisalo, J; Brown, A J; Ikonen, E; Gylling, H.
Afiliação
  • Simonen P; From the, Heart and Lung Center, Cardiology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
  • Li S; Department of Anatomy and Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
  • Chua NK; Minerva Foundation Institute for Medical Research, Helsinki, Finland.
  • Lampi AM; School of Biotechnology and Biomolecular Sciences, UNSW Sydney, Sydney, NSW, Australia.
  • Piironen V; Department of Food and Nutrition, University of Helsinki, Helsinki, Finland.
  • Lommi J; Department of Food and Nutrition, University of Helsinki, Helsinki, Finland.
  • Sinisalo J; From the, Heart and Lung Center, Cardiology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
  • Brown AJ; From the, Heart and Lung Center, Cardiology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
  • Ikonen E; School of Biotechnology and Biomolecular Sciences, UNSW Sydney, Sydney, NSW, Australia.
  • Gylling H; Department of Anatomy and Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
J Intern Med ; 288(5): 560-569, 2020 11.
Article em En | MEDLINE | ID: mdl-32415867
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Arritmias Cardíacas / Colesterol / Oxirredutases atuantes sobre Doadores de Grupo CH-CH / Desmosterol / Amiodarona / Antiarrítmicos / Proteínas do Tecido Nervoso Limite: Female / Humans / Male / Middle aged Idioma: En Revista: J Intern Med Assunto da revista: MEDICINA INTERNA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Finlândia
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Arritmias Cardíacas / Colesterol / Oxirredutases atuantes sobre Doadores de Grupo CH-CH / Desmosterol / Amiodarona / Antiarrítmicos / Proteínas do Tecido Nervoso Limite: Female / Humans / Male / Middle aged Idioma: En Revista: J Intern Med Assunto da revista: MEDICINA INTERNA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Finlândia