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Sorafenib and everolimus in patients with advanced solid tumors and KRAS-mutated NSCLC: A phase I trial with early pharmacodynamic FDG-PET assessment.
Nogova, Lucia; Mattonet, Christian; Scheffler, Matthias; Taubert, Max; Gardizi, Masyar; Sos, Martin L; Michels, Sebastian; Fischer, Rieke N; Limburg, Meike; Abdulla, Diana S Y; Persigehl, Thorsten; Kobe, Carsten; Merkelbach-Bruse, Sabine; Franklin, Jeremy; Backes, Heiko; Schnell, Roland; Behringer, Dirk; Kaminsky, Britta; Eichstaedt, Martina; Stelzer, Christoph; Kinzig, Martina; Sörgel, Fritz; Tian, Yingying; Junge, Lisa; Suleiman, Ahmed A; Frechen, Sebastian; Rokitta, Dennis; Ouyang, Dongsheng; Fuhr, Uwe; Buettner, Reinhard; Wolf, Jürgen.
Afiliação
  • Nogova L; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Lung Cancer Group, University of Cologne, Cologne, Germany.
  • Mattonet C; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Lung Cancer Group, University of Cologne, Cologne, Germany.
  • Scheffler M; Onkologische Praxis Moers, Moers, Germany.
  • Taubert M; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Lung Cancer Group, University of Cologne, Cologne, Germany.
  • Gardizi M; Faculty of Medicine and University Hospital Cologne, Center for Pharmacology, Department I of Pharmacology, University of Cologne, Cologne, Germany.
  • Sos ML; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Lung Cancer Group, University of Cologne, Cologne, Germany.
  • Michels S; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Lung Cancer Group, University of Cologne, Cologne, Germany.
  • Fischer RN; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Lung Cancer Group, University of Cologne, Cologne, Germany.
  • Limburg M; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Lung Cancer Group, University of Cologne, Cologne, Germany.
  • Abdulla DSY; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Lung Cancer Group, University of Cologne, Cologne, Germany.
  • Persigehl T; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Lung Cancer Group, University of Cologne, Cologne, Germany.
  • Kobe C; Faculty of Medicine and University Hospital Cologne, Institute for Diagnostics und Intervention Radiology, University of Cologne, Cologne, Germany.
  • Merkelbach-Bruse S; Faculty of Medicine and University Hospital Cologne, Department for Nuclear Medicine, University of Cologne, Cologne, Germany.
  • Franklin J; Faculty of Medicine and University Hospital Cologne, Institute for Pathology, University of Cologne, Cologne, Germany.
  • Backes H; Faculty of Medicine, Institute for Medical Statistics and Bioinformatics, University of Cologne, Cologne, Germany.
  • Schnell R; Max Planck Institute for Metabolism Research, Cologne, Germany.
  • Behringer D; Praxis for Medical Oncology and Haematology (PIOH), Frechen, Germany.
  • Kaminsky B; Heamatology and Oncology, Augusta Hospital, Bochum, Germany.
  • Eichstaedt M; Bethanien Hospital, Solingen, Germany.
  • Stelzer C; Medical Oncology and Haematology, St. Marien Hospital, Düren, Germany.
  • Kinzig M; Institute for Biomedical and Pharmaceutical Research (IBMP), Nürnberg, Germany.
  • Sörgel F; Institute for Biomedical and Pharmaceutical Research (IBMP), Nürnberg, Germany.
  • Tian Y; Institute for Biomedical and Pharmaceutical Research (IBMP), Nürnberg, Germany.
  • Junge L; Faculty of Medicine and University Hospital Cologne, Center for Pharmacology, Department I of Pharmacology, University of Cologne, Cologne, Germany.
  • Suleiman AA; Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, China.
  • Frechen S; Faculty of Medicine and University Hospital Cologne, Center for Pharmacology, Department I of Pharmacology, University of Cologne, Cologne, Germany.
  • Rokitta D; Faculty of Medicine and University Hospital Cologne, Center for Pharmacology, Department I of Pharmacology, University of Cologne, Cologne, Germany.
  • Ouyang D; Faculty of Medicine and University Hospital Cologne, Center for Pharmacology, Department I of Pharmacology, University of Cologne, Cologne, Germany.
  • Fuhr U; Faculty of Medicine and University Hospital Cologne, Center for Pharmacology, Department I of Pharmacology, University of Cologne, Cologne, Germany.
  • Buettner R; Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, China.
  • Wolf J; Hunan Key Laboratory for Bioanalysis of Complex Matrix Samples, Changsha, China.
Cancer Med ; 9(14): 4991-5007, 2020 07.
Article em En | MEDLINE | ID: mdl-32436621
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Protocolos de Quimioterapia Combinada Antineoplásica / Proteínas Proto-Oncogênicas p21(ras) / Carcinoma Pulmonar de Células não Pequenas / Fluordesoxiglucose F18 / Tomografia por Emissão de Pósitrons / Everolimo / Sorafenibe / Neoplasias Pulmonares Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Cancer Med Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Protocolos de Quimioterapia Combinada Antineoplásica / Proteínas Proto-Oncogênicas p21(ras) / Carcinoma Pulmonar de Células não Pequenas / Fluordesoxiglucose F18 / Tomografia por Emissão de Pósitrons / Everolimo / Sorafenibe / Neoplasias Pulmonares Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Cancer Med Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha