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Endogenous levels of 1-O-acylceramides increase upon acidic ceramidase deficiency and decrease due to loss of Dgat1 in a tissue-dependent manner.
Bayerle, Aline; Marsching, Christian; Rabionet, Mariona; Dworski, Shaalee; Kamani, Mustafa A; Chitraju, Chandramohan; Gluchowski, Nina L; Gabriel, Katlyn R; Herzer, Silke; Jennemann, Richard; Levade, Thierry; Medin, Jeffrey A; Sandhoff, Roger.
Afiliação
  • Bayerle A; Lipid Pathobiochemistry Group, German Cancer Research Center, Heidelberg, Germany.
  • Marsching C; Lipid Pathobiochemistry Group, German Cancer Research Center, Heidelberg, Germany; Center for Applied Research in Biomedical Mass Spectrometry (ABIMAS), Mannheim, Germany; Instrumental Analytics and Bioanalytics, Mannheim University of Applied Sciences, Mannheim, Germany; Center for Mass Spectrometr
  • Rabionet M; Lipid Pathobiochemistry Group, German Cancer Research Center, Heidelberg, Germany.
  • Dworski S; Institute of Medical Sciences, University of Toronto, Toronto, Ontario, Canada.
  • Kamani MA; University Health Network, Toronto, Canada.
  • Chitraju C; Department of Genetics and Complex Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.
  • Gluchowski NL; Department of Genetics and Complex Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Department of Cell Biology, Harvard Medical School, Boston, MA, USA; Division of Gastroenterology and Nutrition, Boston Children's Hospital, Boston, MA, USA.
  • Gabriel KR; Department of Genetics and Complex Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Department of Cell Biology, Harvard Medical School, Boston, MA, USA; Howard Hughes Medical Institute, Boston, MA, USA.
  • Herzer S; Lipid Pathobiochemistry Group, German Cancer Research Center, Heidelberg, Germany.
  • Jennemann R; Lipid Pathobiochemistry Group, German Cancer Research Center, Heidelberg, Germany.
  • Levade T; Laboratoire de Biochimie Métabolique, Institut Fédératif de Biologie, CHU Purpan, INSERM UMR1037 CRCT, Toulouse, France.
  • Medin JA; Institute of Medical Sciences, University of Toronto, Toronto, Ontario, Canada; University Health Network, Toronto, Canada; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada; Medical College of Wisconsin, Milwaukee, WI 53226, USA.
  • Sandhoff R; Lipid Pathobiochemistry Group, German Cancer Research Center, Heidelberg, Germany; Center for Applied Research in Biomedical Mass Spectrometry (ABIMAS), Mannheim, Germany. Electronic address: r.sandhoff@dkfz.de.
Article em En | MEDLINE | ID: mdl-32474112

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ceramidas / Diacilglicerol O-Aciltransferase / Metabolismo dos Lipídeos / Lipogranulomatose de Farber Limite: Animals Idioma: En Revista: Biochim Biophys Acta Mol Cell Biol Lipids Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ceramidas / Diacilglicerol O-Aciltransferase / Metabolismo dos Lipídeos / Lipogranulomatose de Farber Limite: Animals Idioma: En Revista: Biochim Biophys Acta Mol Cell Biol Lipids Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha