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Secondary Osteosarcoma After Bone Marrow Transplant: An Aggressive Disease.
Pierobon, Marta; Mercolini, Federico; Affinita, Maria Carmen; Tombolan, Lucia; Battisti, Laura; Bisogno, Gianni.
Afiliação
  • Pierobon M; Hematology and Oncology Unit, Department of Women's and Children's Health, University of Padua, Padua, Italy.
  • Mercolini F; Pediatric Hematology and Oncology Unit, Department of Pediatrics, Bolzano Hospital, Bolzano, Italy.
  • Affinita MC; Hematology and Oncology Unit, Department of Women's and Children's Health, University of Padua, Padua, Italy.
  • Tombolan L; Fondazione Istituto di Ricerca Pediatrica Città della Speranza, Padua, Italy.
  • Battisti L; Pediatric Hematology and Oncology Unit, Department of Pediatrics, Bolzano Hospital, Bolzano, Italy.
  • Bisogno G; Hematology and Oncology Unit, Department of Women's and Children's Health, University of Padua, Padua, Italy.
J Adolesc Young Adult Oncol ; 9(6): 672-675, 2020 12.
Article em En | MEDLINE | ID: mdl-32486931
ABSTRACT
We describe three children who developed an osteosarcoma after receiving treatment for acute lymphoblastic leukemia, which included an allogeneic bone marrow transplant (BMT). We discuss the therapeutic options. None of the patients responded to conventional chemotherapy, but one patient given regorafenib showed a temporary response. We conclude that osteosarcoma after BMT has an aggressive course and it is worth further investigating multikinase inhibitors in this setting.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteossarcoma / Transplante de Medula Óssea Limite: Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: J Adolesc Young Adult Oncol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Itália
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteossarcoma / Transplante de Medula Óssea Limite: Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: J Adolesc Young Adult Oncol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Itália