Case report of persistent elevation of ßhCG in a nonpregnant woman: A diagnostic puzzle.
J Obstet Gynaecol Res
; 46(8): 1465-1469, 2020 Aug.
Article
em En
| MEDLINE
| ID: mdl-32500568
ABSTRACT
Detectable serum levels of beta subunit of human chorionic gonadotropin (ßhCG) in nonpregnant, perimenopausal women bring confusion in both clinician and patient and could lead to unnecessary diagnostic and therapeutic procedures. A 45-year-old woman with the continuous elevation of ßhCG underwent hysteroscopy, two laparoscopic surgeries, two explorative uterine cavity curettages and three cycles of cytostatic therapy. No ultrasonographic, macroscopic or histological signs of pregnancy, both uterine and ectopic or gestational trophoblastic disease were found. Both radiographic and computed tomography reports ruled out the presence of a nongynecological neoplasm. All recommended steps were taken for confirmation or ruling out the possibility of heterophile antibodies interference, but the results were not absolute. Finally, the referent laboratory confirmed the presence of the antibodies, but their exact type remains unknown. This case underlines the importance of the universally accepted protocol in the cases of persistent ßhCG elevation in nonpregnant, perimenopausal women.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Gonadotropina Coriônica Humana Subunidade beta
/
Doença Trofoblástica Gestacional
Tipo de estudo:
Diagnostic_studies
/
Guideline
Limite:
Female
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Humans
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Middle aged
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Pregnancy
Idioma:
En
Revista:
J Obstet Gynaecol Res
Assunto da revista:
GINECOLOGIA
/
OBSTETRICIA
Ano de publicação:
2020
Tipo de documento:
Article