Identification of important genes and drug repurposing based on clinical-centered analysis across human cancers.

Li, Ying; Dong, Ya-Ping; Qian, You-Wen; Yu, Le-Xing; Wen, Wen; Cui, Xiu-Liang; Wang, Hong-Yang

Li, Ying; Dong, Ya-Ping; Qian, You-Wen; Yu, Le-Xing; Wen, Wen; Cui, Xiu-Liang; Wang, Hong-Yang.

Afiliação

Li Y; National Center for Liver Cancer, Second Military Medical University, Shanghai, 200438, China.
Dong YP; National Center for Liver Cancer, Second Military Medical University, Shanghai, 200438, China.
Qian YW; The Graduate School of Fujian Medical University, Fuzhou, 350122, China.
Yu LX; Department of Pathology, Eastern Hepatobiliary Surgery Hospital/Institute, Second Military Medical University, Shanghai, 200433, China.
Wen W; National Center for Liver Cancer, Second Military Medical University, Shanghai, 200438, China.
Cui XL; National Center for Liver Cancer, Second Military Medical University, Shanghai, 200438, China.
Wang HY; International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital/Institute, Second Military Medical University, Shanghai, 200433, China.

Acta Pharmacol Sin ; 42(2): 282-289, 2021 Feb.

Article em En | MEDLINE | ID: mdl-32555508

Assuntos

Antineoplásicos/farmacologia; Reposicionamento de Medicamentos/métodos; Neoplasias/genética; Bases de Dados Factuais; Desenvolvimento de Medicamentos/métodos; Humanos; Terapia de Alvo Molecular; Mutação; Neoplasias/patologia; Sobrevida

Palavras-chave

clinical correlation; drug repurposing; network analysis; pancancer.; somatic mutation; survival outcomes

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Reposicionamento de Medicamentos / Neoplasias / Antineoplásicos Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Humans Idioma: En Revista: Acta Pharmacol Sin Assunto da revista: FARMACOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

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