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Cannabis Abuse or Dependence and Post-operative Outcomes After Appendectomy and Cholecystectomy.
Anderson, Spencer R; Wimalawansa, Sunishka M; Markov, Nickolay P; Fox, Justin P.
Afiliação
  • Anderson SR; Department of Plastic Surgery, Wright State University, Boonshoft School of Medicine, Dayton, Ohio. Electronic address: spencer.anderson@wright.edu.
  • Wimalawansa SM; Department of Plastic Surgery, Wright State University, Boonshoft School of Medicine, Dayton, Ohio.
  • Markov NP; Surgical Operations Squadron, 88(th) Medical Group, Wright Patterson Medical Center, Wright Patterson AFB, Ohio.
  • Fox JP; Department of Plastic Surgery, Wright State University, Boonshoft School of Medicine, Dayton, Ohio; Surgical Operations Squadron, 88(th) Medical Group, Wright Patterson Medical Center, Wright Patterson AFB, Ohio.
J Surg Res ; 255: 233-239, 2020 11.
Article em En | MEDLINE | ID: mdl-32570125
BACKGROUND: Though cannabis is gaining broader acceptance among society and a noted increase in legalization, little is known regarding its impact on post-operative outcomes. We conducted this study to quantify the relationship between cannabis abuse or dependence (CbAD) on post-operative outcomes after cholecystectomy and appendectomy. METHODS: Using the 2013-2015 Nationwide Readmissions Database, we identified discharges associated with cholecystectomy or appendectomy from January 2013-August 2015. Patients were grouped by CbAD history. The primary outcomes were length of stay, serious adverse events, home discharge, and 30-day readmission. Propensity-score matching was used to account for differences between groups and all statistics accounted for the matched sample. RESULTS: The final sample included 3288 patients with a CbAD history matched 1:1 to patients without a CbAD history (total sample = 6576). After matching, acceptable balance was achieved in clinical characteristics between groups. In the cholecystectomy cohort (n = 1707 pairs), CbAD patients had longer hospitalizations (3.5 versus 3.2 d, P 0.003) and similar rates of serious adverse events (6.1 versus 4.8, P 0.092), home discharge (96.1 vs 96.2, P 0.855), and readmission (8.3 versus 6.9, P 0.137). In the appendectomy cohort (n = 1581 pairs), CbAD patients had longer hospital stays (2.7 versus 2.5 d, P 0.024); more frequent serious adverse events (5.0 versus 3.5, P 0.041); and similar home discharge (96.8 vs 97.3, P 0.404) and readmission (5.4 versus 5.1, P 0.639) rates. CONCLUSIONS: Patients with a history of CbAD in the cholecystectomy and appendectomy cohorts had slightly longer hospital stays, and patients with a history of CbAD in the appendectomy group displayed a slight increase in adverse events, but otherwise similar clinical outcomes without clinically significant increases in complications compared to patients without this history.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Apendicectomia / Complicações Pós-Operatórias / Colecistectomia / Abuso de Maconha Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: J Surg Res Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Apendicectomia / Complicações Pós-Operatórias / Colecistectomia / Abuso de Maconha Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: J Surg Res Ano de publicação: 2020 Tipo de documento: Article