MiR-126-5p promotes contractile switching of aortic smooth muscle cells by targeting VEPH1 and alleviates Ang II-induced abdominal aortic aneurysm in mice.

Shi, Xiaofeng; Ma, Wei; Pan, Yongquan; Li, Yongqi; Wang, Han; Pan, Shuang; Tian, Yu; Xu, Caiming; Li, Lei

Shi, Xiaofeng; Ma, Wei; Pan, Yongquan; Li, Yongqi; Wang, Han; Pan, Shuang; Tian, Yu; Xu, Caiming; Li, Lei.

Afiliação

Shi X; Department of Emergency, Tianjin First Center Hospital, Tianjin, 300192, People's Republic of China.
Ma W; Department of Anatomy, Dalian Medical University, Dalian, 116044, Liaoning, People's Republic of China.
Pan Y; Department of Vascular Surgery, The Second Affiliated Hospital of Dalian Medical University, Dalian, 116027, Liaoning, People's Republic of China.
Li Y; Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, 3050005, Japan.
Wang H; Department of Vascular Surgery, Dalian University Affiliated Xinhua Hospital, Dalian, 116021, Liaoning, People's Republic of China.
Pan S; Department of Physiology, School of Basic Medicine, Jinzhou Medical University, Jinzhou, 121000, Liaoning, People's Republic of China.
Tian Y; Department of Vascular Surgery, The Second Affiliated Hospital of Dalian Medical University, Dalian, 116027, Liaoning, People's Republic of China.
Xu C; Department of General Surgery, The First Affiliated Hospital of Dalian Medical University, Dalian, 116011, Liaoning, China.
Li L; Department of Vascular Surgery, The Second Affiliated Hospital of Dalian Medical University, Dalian, 116027, Liaoning, People's Republic of China. lilei_dmu@163.com.

Lab Invest ; 100(12): 1564-1574, 2020 12.

Article em En | MEDLINE | ID: mdl-32612287

Assuntos

Angiotensina II/metabolismo; Aorta Abdominal; MicroRNAs; Músculo Liso Vascular; Proteínas do Tecido Nervoso/metabolismo; Animais; Aorta Abdominal/citologia; Aorta Abdominal/metabolismo; Aneurisma da Aorta Abdominal/metabolismo; Diferenciação Celular/genética; Células Cultivadas; Masculino; Camundongos; Camundongos Transgênicos; MicroRNAs/genética; MicroRNAs/metabolismo; Músculo Liso Vascular/citologia; Músculo Liso Vascular/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Aorta Abdominal / Angiotensina II / MicroRNAs / Músculo Liso Vascular / Proteínas do Tecido Nervoso Limite: Animals Idioma: En Revista: Lab Invest Ano de publicação: 2020 Tipo de documento: Article

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