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Topoisomerase Inhibitors Addressing Fluoroquinolone Resistance in Gram-Negative Bacteria.
Skepper, Colin K; Armstrong, Duncan; Balibar, Carl J; Bauer, Daniel; Bellamacina, Cornelia; Benton, Bret M; Bussiere, Dirksen; De Pascale, Gianfranco; De Vicente, Javier; Dean, Charles R; Dhumale, Bhavesh; Fisher, L Mark; Fuller, John; Fulsunder, Mangesh; Holder, Lauren M; Hu, Cheng; Kantariya, Bhavin; Lapointe, Guillaume; Leeds, Jennifer A; Li, Xiaolin; Lu, Peichao; Lvov, Anatoli; Ma, Sylvia; Madhavan, Shravanthi; Malekar, Swapnil; McKenney, David; Mergo, Wosenu; Metzger, Louis; Moser, Heinz E; Mutnick, Daniel; Noeske, Jonas; Osborne, Colin; Patel, Ashish; Patel, Darshit; Patel, Tushar; Prajapati, Krunal; Prosen, Katherine R; Reck, Folkert; Richie, Daryl L; Rico, Alice; Sanderson, Mark R; Satasia, Shailesh; Sawyer, William S; Selvarajah, Jogitha; Shah, Nirav; Shanghavi, Kartik; Shu, Wei; Thompson, Katherine V; Traebert, Martin; Vala, Anand.
Afiliação
  • Skepper CK; Novartis Institutes for BioMedical Research, Emeryville, California 94608, United States.
  • Armstrong D; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States.
  • Balibar CJ; Novartis Institutes for BioMedical Research, Emeryville, California 94608, United States.
  • Bauer D; Novartis Institutes for BioMedical Research, 4002 Basel, Switzerland.
  • Bellamacina C; Novartis Institutes for BioMedical Research, Emeryville, California 94608, United States.
  • Benton BM; Novartis Institutes for BioMedical Research, Emeryville, California 94608, United States.
  • Bussiere D; Novartis Institutes for BioMedical Research, Emeryville, California 94608, United States.
  • De Pascale G; Novartis Institutes for BioMedical Research, Emeryville, California 94608, United States.
  • De Vicente J; Novartis Institutes for BioMedical Research, Emeryville, California 94608, United States.
  • Dean CR; Novartis Institutes for BioMedical Research, Emeryville, California 94608, United States.
  • Dhumale B; Piramal Discovery Solutions, Pharmaceutical Special Economic Zone, Sarkhej Bavla Highway, Ahmedabad, Gujarat 382213, India.
  • Fisher LM; Molecular and Clinical Sciences Research Institute, St George's University of London, London SW17 0RE, U.K.
  • Fuller J; Novartis Institutes for BioMedical Research, Emeryville, California 94608, United States.
  • Fulsunder M; Piramal Discovery Solutions, Pharmaceutical Special Economic Zone, Sarkhej Bavla Highway, Ahmedabad, Gujarat 382213, India.
  • Holder LM; Novartis Institutes for BioMedical Research, Emeryville, California 94608, United States.
  • Hu C; Novartis Institutes for BioMedical Research, Emeryville, California 94608, United States.
  • Kantariya B; Piramal Discovery Solutions, Pharmaceutical Special Economic Zone, Sarkhej Bavla Highway, Ahmedabad, Gujarat 382213, India.
  • Lapointe G; Novartis Institutes for BioMedical Research, Emeryville, California 94608, United States.
  • Leeds JA; Novartis Institutes for BioMedical Research, Emeryville, California 94608, United States.
  • Li X; Novartis Institutes for BioMedical Research, Emeryville, California 94608, United States.
  • Lu P; Novartis Institutes for BioMedical Research, Emeryville, California 94608, United States.
  • Lvov A; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States.
  • Ma S; Novartis Institutes for BioMedical Research, Emeryville, California 94608, United States.
  • Madhavan S; Novartis Institutes for BioMedical Research, Emeryville, California 94608, United States.
  • Malekar S; Novartis Institutes for BioMedical Research, Emeryville, California 94608, United States.
  • McKenney D; Novartis Institutes for BioMedical Research, Emeryville, California 94608, United States.
  • Mergo W; Novartis Institutes for BioMedical Research, Emeryville, California 94608, United States.
  • Metzger L; Novartis Institutes for BioMedical Research, Emeryville, California 94608, United States.
  • Moser HE; Novartis Institutes for BioMedical Research, Emeryville, California 94608, United States.
  • Mutnick D; Novartis Institutes for BioMedical Research, Emeryville, California 94608, United States.
  • Noeske J; Novartis Institutes for BioMedical Research, Emeryville, California 94608, United States.
  • Osborne C; Novartis Institutes for BioMedical Research, Emeryville, California 94608, United States.
  • Patel A; Piramal Discovery Solutions, Pharmaceutical Special Economic Zone, Sarkhej Bavla Highway, Ahmedabad, Gujarat 382213, India.
  • Patel D; Piramal Discovery Solutions, Pharmaceutical Special Economic Zone, Sarkhej Bavla Highway, Ahmedabad, Gujarat 382213, India.
  • Patel T; Piramal Discovery Solutions, Pharmaceutical Special Economic Zone, Sarkhej Bavla Highway, Ahmedabad, Gujarat 382213, India.
  • Prajapati K; Piramal Discovery Solutions, Pharmaceutical Special Economic Zone, Sarkhej Bavla Highway, Ahmedabad, Gujarat 382213, India.
  • Prosen KR; Novartis Institutes for BioMedical Research, Emeryville, California 94608, United States.
  • Reck F; Novartis Institutes for BioMedical Research, Emeryville, California 94608, United States.
  • Richie DL; Novartis Institutes for BioMedical Research, Emeryville, California 94608, United States.
  • Rico A; Novartis Institutes for BioMedical Research, Emeryville, California 94608, United States.
  • Sanderson MR; Randall Centre for Cell and Molecular Biophysics, King's College, Guy's Campus, London Bridge, London SE1 1UL, U.K.
  • Satasia S; Piramal Discovery Solutions, Pharmaceutical Special Economic Zone, Sarkhej Bavla Highway, Ahmedabad, Gujarat 382213, India.
  • Sawyer WS; Novartis Institutes for BioMedical Research, Emeryville, California 94608, United States.
  • Selvarajah J; Molecular and Clinical Sciences Research Institute, St George's University of London, London SW17 0RE, U.K.
  • Shah N; Piramal Discovery Solutions, Pharmaceutical Special Economic Zone, Sarkhej Bavla Highway, Ahmedabad, Gujarat 382213, India.
  • Shanghavi K; Piramal Discovery Solutions, Pharmaceutical Special Economic Zone, Sarkhej Bavla Highway, Ahmedabad, Gujarat 382213, India.
  • Shu W; Novartis Institutes for BioMedical Research, Emeryville, California 94608, United States.
  • Thompson KV; Novartis Institutes for BioMedical Research, Emeryville, California 94608, United States.
  • Traebert M; Novartis Institutes for BioMedical Research, 4002 Basel, Switzerland.
  • Vala A; Piramal Discovery Solutions, Pharmaceutical Special Economic Zone, Sarkhej Bavla Highway, Ahmedabad, Gujarat 382213, India.
J Med Chem ; 63(14): 7773-7816, 2020 07 23.
Article em En | MEDLINE | ID: mdl-32634310
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fluoroquinolonas / Farmacorresistência Bacteriana / Inibidores da Topoisomerase II / Bactérias Gram-Negativas / Antibacterianos Limite: Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fluoroquinolonas / Farmacorresistência Bacteriana / Inibidores da Topoisomerase II / Bactérias Gram-Negativas / Antibacterianos Limite: Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos