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Structure guided design and synthesis of furyl thiazolidinedione derivatives as inhibitors of GLUT 1 and GLUT 4, and evaluation of their anti-leukemic potential.
Tilekar, Kalpana; Upadhyay, Neha; Hess, Jessica D; Macias, Lucasantiago Henze; Mrowka, Piotr; Aguilera, Renato J; Meyer-Almes, Franz-Josef; Iancu, Cristina V; Choe, Jun-Yong; Ramaa, C S.
Afiliação
  • Tilekar K; Department of Pharmaceutical Chemistry, Bharati Vidyapeeth's College of Pharmacy, Navi Mumbai, Maharashtra, India.
  • Upadhyay N; Department of Pharmaceutical Chemistry, Bharati Vidyapeeth's College of Pharmacy, Navi Mumbai, Maharashtra, India.
  • Hess JD; The Cytometry, Screening and Imaging Core Facility & Border Biomedical Research Center & Department of Biological Sciences, The University of Texas at El Paso, El Paso, TX, USA.
  • Macias LH; The Cytometry, Screening and Imaging Core Facility & Border Biomedical Research Center & Department of Biological Sciences, The University of Texas at El Paso, El Paso, TX, USA.
  • Mrowka P; Department of Biophysics and Human Physiology, Medical University of Warsaw, Chalubinskiego, Warsaw, Poland.
  • Aguilera RJ; The Cytometry, Screening and Imaging Core Facility & Border Biomedical Research Center & Department of Biological Sciences, The University of Texas at El Paso, El Paso, TX, USA.
  • Meyer-Almes FJ; Department of Chemical Engineering and Biotechnology, University of Applied Sciences, Darmstadt, Germany.
  • Iancu CV; East Carolina Diabetes and Obesity Institute, Department of Chemistry, East Carolina University, Greenville, NC, USA.
  • Choe JY; East Carolina Diabetes and Obesity Institute, Department of Chemistry, East Carolina University, Greenville, NC, USA; Department of Biochemistry and Molecular Biology, The Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, IL, USA. Electronic address: choej1
  • Ramaa CS; Department of Pharmaceutical Chemistry, Bharati Vidyapeeth's College of Pharmacy, Navi Mumbai, Maharashtra, India. Electronic address: sinharamaa@yahoo.in.
Eur J Med Chem ; 202: 112603, 2020 Sep 15.
Article em En | MEDLINE | ID: mdl-32634629
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Tiazolidinedionas / Transportador de Glucose Tipo 1 / Transportador de Glucose Tipo 4 / Antineoplásicos Limite: Animals / Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Índia
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Tiazolidinedionas / Transportador de Glucose Tipo 1 / Transportador de Glucose Tipo 4 / Antineoplásicos Limite: Animals / Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Índia