Multivisceral resection of locally advanced colorectal cancer in an African referral centre.
S Afr J Surg
; 58(2): 64-69, 2020 Jun.
Article
em En
| MEDLINE
| ID: mdl-32644308
ABSTRACT
BACKGROUND:
Colorectal cancer (CRC) is common and often presents with advanced disease in Africa. Multivisceral resection (MVR) improves survival in locally advanced (T4b) CRC. The aim was to describe the management and outcomes of patients with clinical T4b CRC without metastatic disease who underwent MVR.METHODS:
A retrospective review of patients with T4 CRC who underwent MVR between January 2008 and December 2013.RESULTS:
Four hundred and ninety-four patients were included. Of the 158 with suspected T4 cancer, 44 had MVR, of which one was excluded due to metastases. The mean age was 64 years. The male to female ratio was 11. The most commonly resected extra-colorectal structure was the abdominal wall (21%). The median survival was 68 months (SD 13.9). The 5-year disease free (DFS) and overall survival (OS) were 46% and 55%, respectively. Survival of patients with colon and rectum cancer was similar. Intraoperative tumour spillage, vascular/perineural invasion, and anastomotic leakage were independent predictors of survival.CONCLUSION:
Multivisceral resection of locally advanced (T4b) CRC is feasible in the African context. Complete resection improves survival and should be the goal.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Vísceras
/
Neoplasias Colorretais
/
Parede Abdominal
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Male
/
Middle aged
País/Região como assunto:
Africa
Idioma:
En
Revista:
S Afr J Surg
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
África do Sul