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Etomidate is devoid of genotoxicty and mutagenicity in human lymphocytes and in the Salmonella typhimurium/microsomal activation test.
Cavalcanti, Bruno Coêlho; do Amaral Valente Sá, Lívia Gurgel; de Andrade Neto, João Batista; de Sousa Silva, Antônio Adailson; Rios, Maria Erivanda França; Barreto, Francisco Stefânio; de Oliveira Ferreira, José Roberto; da Silva, Cecília Rocha; Barroso, Fátima Daiana; Magalhães, Hemerson Iury Ferreira; Nobre, Hélio Vitoriano; de Moraes, Manoel Odorico.
Afiliação
  • Cavalcanti BC; Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil; Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, CE, Brazil. Electronic address: bccavalcanti@cnpq.b.
  • do Amaral Valente Sá LG; Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil; School of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil.
  • de Andrade Neto JB; Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil; Christus University Center (UNICHRISTUS), Fortaleza, CE, Brazil; School of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil.
  • de Sousa Silva AA; Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, CE, Brazil.
  • Rios MEF; Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil.
  • Barreto FS; Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, CE, Brazil.
  • de Oliveira Ferreira JR; School of Medical Sciences, State University of Health Sciences of Alagoas (UNCISAL), AL, Brazil.
  • da Silva CR; Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil; School of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil.
  • Barroso FD; School of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil.
  • Magalhães HIF; Department of Pharmaceutical Sciences, Federal University of Paraiba, João Pessoa, PB, Brazil.
  • Nobre HV; Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil; School of Pharmacy, Laboratory for Bioprospection of Antimicrobial Molecules (LABIMAN), Federal University of Ceará, Fortaleza, CE, Brazil.
  • de Moraes MO; Drug Research and Development Center, Federal University of Ceará, Fortaleza, CE, Brazil; Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, CE, Brazil.
Toxicol In Vitro ; 68: 104946, 2020 Oct.
Article em En | MEDLINE | ID: mdl-32679257
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Salmonella typhimurium / Linfócitos / Etomidato / Hipnóticos e Sedativos Limite: Adult / Animals / Humans Idioma: En Revista: Toxicol In Vitro Assunto da revista: TOXICOLOGIA Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Salmonella typhimurium / Linfócitos / Etomidato / Hipnóticos e Sedativos Limite: Adult / Animals / Humans Idioma: En Revista: Toxicol In Vitro Assunto da revista: TOXICOLOGIA Ano de publicação: 2020 Tipo de documento: Article