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Tumour-reprogrammed stromal BCAT1 fuels branched-chain ketoacid dependency in stromal-rich PDAC tumours.
Zhu, Ziwen; Achreja, Abhinav; Meurs, Noah; Animasahun, Olamide; Owen, Sarah; Mittal, Anjali; Parikh, Pooja; Lo, Ting-Wen; Franco-Barraza, Janusz; Shi, Jiaqi; Gunchick, Valerie; Sherman, Mara H; Cukierman, Edna; Pickering, Andrew M; Maitra, Anirban; Sahai, Vaibhav; Morgan, Meredith A; Nagrath, Sunitha; Lawrence, Theodore S; Nagrath, Deepak.
Afiliação
  • Zhu Z; Laboratory for Systems Biology of Human Diseases, University of Michigan, Ann Arbor, MI, USA.
  • Achreja A; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.
  • Meurs N; Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA.
  • Animasahun O; Laboratory for Systems Biology of Human Diseases, University of Michigan, Ann Arbor, MI, USA.
  • Owen S; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.
  • Mittal A; Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA.
  • Parikh P; Laboratory for Systems Biology of Human Diseases, University of Michigan, Ann Arbor, MI, USA.
  • Lo TW; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.
  • Franco-Barraza J; Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA.
  • Shi J; Laboratory for Systems Biology of Human Diseases, University of Michigan, Ann Arbor, MI, USA.
  • Gunchick V; Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA.
  • Sherman MH; Department of Chemical Engineering, University of Michigan, Ann Arbor, MI, USA.
  • Cukierman E; Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA.
  • Pickering AM; Department of Chemical Engineering, University of Michigan, Ann Arbor, MI, USA.
  • Maitra A; Laboratory for Systems Biology of Human Diseases, University of Michigan, Ann Arbor, MI, USA.
  • Sahai V; Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA.
  • Morgan MA; Department of Chemical Engineering, University of Michigan, Ann Arbor, MI, USA.
  • Nagrath S; Laboratory for Systems Biology of Human Diseases, University of Michigan, Ann Arbor, MI, USA.
  • Lawrence TS; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.
  • Nagrath D; Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA.
Nat Metab ; 2(8): 775-792, 2020 08.
Article em En | MEDLINE | ID: mdl-32694827

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Células Estromais / Carcinoma Ductal Pancreático / Transaminases / Cetoácidos Limite: Humans Idioma: En Revista: Nat Metab Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Células Estromais / Carcinoma Ductal Pancreático / Transaminases / Cetoácidos Limite: Humans Idioma: En Revista: Nat Metab Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos