Burden of prematurity-associated recurrent wheezing: caregiver missed work in the D-Wheeze trial.
J Perinatol
; 41(1): 69-76, 2021 01.
Article
em En
| MEDLINE
| ID: mdl-32694857
ABSTRACT
OBJECTIVE:
This study describes the burden of prematurity-associated wheezing in black infants with respect to caregiver missed work. STUDYDESIGN:
We analyzed data from the D-Wheeze trial (ClinicalTrials.gov identifier NCT01601847). Black infants between 28-0/7 to 36-6/7 weeks' gestational age at birth receiving <28 days of supplemental oxygen were enrolled. The primary outcome was missed work to care for the infant in the first year.RESULTS:
147/277 (53.1%) infants had caregivers who reported time off. In an adjusted model, vitamin D supplementation (OR 0.52 [95% CI 0.30-0.89]; P = 0.018), recurrent wheeze (OR 2.26 [95% CI, 1.15-4.44]; P = 0.018), and other children in the household <5 years old (OR 0.45 [95% CI 0.26-0.78]; P = 0.004) were significantly associated with caregiver missed work.CONCLUSIONS:
Black premature infants had a significant burden of caregiver missed work, emphasizing the impact of prematurity-associated wheezing.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cuidadores
/
Doenças do Prematuro
Tipo de estudo:
Etiology_studies
/
Risk_factors_studies
Limite:
Child
/
Child, preschool
/
Humans
/
Infant
/
Newborn
Idioma:
En
Revista:
J Perinatol
Assunto da revista:
PERINATOLOGIA
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Estados Unidos