Heritable risk for severe anaphylaxis associated with increased &#945;-tryptase-encoding germline copy number at TPSAB1.

Lyons, Jonathan J; Chovanec, Jack; O'Connell, Michael P; Liu, Yihui; Selb, Julij; Zanotti, Roberta; Bai, Yun; Kim, Jiwon; Le, Quang T; DiMaggio, Tom; Schwartz, Lawrence B; Komarow, Hirsh D; Rijavec, Matija; Carter, Melody C; Milner, Joshua D; Bonadonna, Patrizia; Metcalfe, Dean D; Korosec, Peter

Heritable risk for severe anaphylaxis associated with increased α-tryptase-encoding germline copy number at TPSAB1.

Lyons, Jonathan J; Chovanec, Jack; O'Connell, Michael P; Liu, Yihui; Selb, Julij; Zanotti, Roberta; Bai, Yun; Kim, Jiwon; Le, Quang T; DiMaggio, Tom; Schwartz, Lawrence B; Komarow, Hirsh D; Rijavec, Matija; Carter, Melody C; Milner, Joshua D; Bonadonna, Patrizia; Metcalfe, Dean D; Korosec, Peter.

Afiliação

Lyons JJ; Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md. Electronic address: jonathan.lyons@nih.gov.
Chovanec J; Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.
O'Connell MP; Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.
Liu Y; Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.
Selb J; University Clinic of Respiratory and Allergic Diseases, Golnik, Slovenia.
Zanotti R; Department of Medicine, Section of Hematology, Verona, Italy.
Bai Y; Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.
Kim J; Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.
Le QT; Department of Internal Medicine, Virginia Commonwealth University, Richmond, Va.
DiMaggio T; Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.
Schwartz LB; Department of Internal Medicine, Virginia Commonwealth University, Richmond, Va.
Komarow HD; Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.
Rijavec M; University Clinic of Respiratory and Allergic Diseases, Golnik, Slovenia.
Carter MC; Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.
Milner JD; Division of Allergy, Immunology and Rheumatology, Columbia University, New York, New York.
Bonadonna P; Allergy Unit, Verona University Hospital, Verona, Italy.
Metcalfe DD; Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.
Korosec P; University Clinic of Respiratory and Allergic Diseases, Golnik, Slovenia.

J Allergy Clin Immunol ; 147(2): 622-632, 2021 02.

Article em En | MEDLINE | ID: mdl-32717252

Assuntos

Anafilaxia/genética; Mastocitose Sistêmica/genética; Triptases/sangue; Adolescente; Adulto; Idoso; Venenos de Artrópodes/efeitos adversos; Criança; Variações do Número de Cópias de DNA; Feminino; Predisposição Genética para Doença; Genótipo; Humanos; Masculino; Pessoa de Meia-Idade; Triptases/genética; Adulto Jovem

Palavras-chave

Mastocytosis; hereditary α-tryptasemia; hypersensitivity; idiopathic anaphylaxis; mast cell activation; venom

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mastocitose Sistêmica / Triptases / Anafilaxia Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Child / Female / Humans / Male / Middle aged Idioma: En Revista: J Allergy Clin Immunol Ano de publicação: 2021 Tipo de documento: Article

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