Identification of novel candidate genes in heterotaxy syndrome patients with congenital heart diseases by whole exome sequencing.

Liang, Shuzhang; Shi, Xin; Yu, Chunxiao; Shao, Xuelian; Zhou, Haitao; Li, Xueyu; Chang, Cheng; Lai, Kaa Seng; Ma, Jinmin; Zhang, Ruilin

Liang, Shuzhang; Shi, Xin; Yu, Chunxiao; Shao, Xuelian; Zhou, Haitao; Li, Xueyu; Chang, Cheng; Lai, Kaa Seng; Ma, Jinmin; Zhang, Ruilin.

Afiliação

Liang S; School of Life Sciences, Fudan University, Shanghai, China.
Shi X; Department of Cardiology, Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China; Department of Pediatric Cardiology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China.
Yu C; School of Basic Medical Sciences, Wuhan University, Wuhan, China.
Shao X; School of Life Sciences, Fudan University, Shanghai, China.
Zhou H; School of Basic Medical Sciences, Wuhan University, Wuhan, China.
Li X; School of Life Sciences, Fudan University, Shanghai, China.
Chang C; School of Basic Medical Sciences, Wuhan University, Wuhan, China.
Lai KS; School of Life Sciences, Fudan University, Shanghai, China.
Ma J; School of Life Sciences, Fudan University, Shanghai, China.
Zhang R; School of Basic Medical Sciences, Wuhan University, Wuhan, China; Hubei Provincial Key Laboratory of Developmentally Originated Disease, Wuhan, China. Electronic address: zhangruilin@whu.edu.cn.

Biochim Biophys Acta Mol Basis Dis ; 1866(12): 165906, 2020 12 01.

Article em En | MEDLINE | ID: mdl-32738303

Assuntos

Proteínas de Ligação a DNA/genética; Sequenciamento do Exoma; Filaminas/genética; Cardiopatias Congênitas/genética; Síndrome de Heterotaxia/genética; Cinesinas/genética; Proteínas de Neoplasias/genética; Proteína GLI1 em Dedos de Zinco/genética; Animais; Antígenos/genética; Estudos de Coortes; Edição de Genes; Humanos; Integrina alfa1/genética; Peixe-Zebra

Palavras-chave

Congenital heart disease; Heterotaxy syndrome; Rare variant; Whole exome sequencing

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cinesinas / Proteínas de Ligação a DNA / Síndrome de Heterotaxia / Filaminas / Proteína GLI1 em Dedos de Zinco / Sequenciamento do Exoma / Cardiopatias Congênitas / Proteínas de Neoplasias Tipo de estudo: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Biochim Biophys Acta Mol Basis Dis Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China

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