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Dual-function chimeric antigen receptor T cells targeting c-Met and PD-1 exhibit potent anti-tumor efficacy in solid tumors.
Yuan, Xingxing; Sun, Zujun; Yuan, Qingyun; Hou, Weihua; Liang, Qiaoyan; Wang, Yuxiong; Mo, Wei; Wang, Huijie; Yu, Min.
Afiliação
  • Yuan X; The Key Laboratory of Metabolism and Molecular Medicine, The Ministry of Education and the Department of Biochemistry and Molecular Biology, School of Basic Medicine, Fudan University, P.O. Box #238, No. 138 Yi Xue Yuan Road, Shanghai, China.
  • Sun Z; The Key Laboratory of Metabolism and Molecular Medicine, The Ministry of Education and the Department of Biochemistry and Molecular Biology, School of Basic Medicine, Fudan University, P.O. Box #238, No. 138 Yi Xue Yuan Road, Shanghai, China.
  • Yuan Q; Department of Clinical Laboratory, Shanghai Tongji Hospital, Tongji University School of Medicine, Shanghai, 200065, China.
  • Hou W; The Key Laboratory of Metabolism and Molecular Medicine, The Ministry of Education and the Department of Biochemistry and Molecular Biology, School of Basic Medicine, Fudan University, P.O. Box #238, No. 138 Yi Xue Yuan Road, Shanghai, China.
  • Liang Q; The Key Laboratory of Metabolism and Molecular Medicine, The Ministry of Education and the Department of Biochemistry and Molecular Biology, School of Basic Medicine, Fudan University, P.O. Box #238, No. 138 Yi Xue Yuan Road, Shanghai, China.
  • Wang Y; The Key Laboratory of Metabolism and Molecular Medicine, The Ministry of Education and the Department of Biochemistry and Molecular Biology, School of Basic Medicine, Fudan University, P.O. Box #238, No. 138 Yi Xue Yuan Road, Shanghai, China.
  • Mo W; The Key Laboratory of Metabolism and Molecular Medicine, The Ministry of Education and the Department of Biochemistry and Molecular Biology, School of Basic Medicine, Fudan University, P.O. Box #238, No. 138 Yi Xue Yuan Road, Shanghai, China.
  • Wang H; The Key Laboratory of Metabolism and Molecular Medicine, The Ministry of Education and the Department of Biochemistry and Molecular Biology, School of Basic Medicine, Fudan University, P.O. Box #238, No. 138 Yi Xue Yuan Road, Shanghai, China.
  • Yu M; Department of Medical Oncology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, No. 270 Dong An Road, Shanghai, China. wanghj98@hotmail.com.
Invest New Drugs ; 39(1): 34-51, 2021 02.
Article em En | MEDLINE | ID: mdl-32772342
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imunoterapia Adotiva / Proteínas Proto-Oncogênicas c-met / Receptor de Morte Celular Programada 1 / Receptores de Antígenos Quiméricos / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Invest New Drugs Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imunoterapia Adotiva / Proteínas Proto-Oncogênicas c-met / Receptor de Morte Celular Programada 1 / Receptores de Antígenos Quiméricos / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Invest New Drugs Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China