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Chronic PERK induction promotes Alzheimer-like neuropathology in Down syndrome: Insights for therapeutic intervention.
Lanzillotta, Chiara; Zuliani, Ilaria; Tramutola, Antonella; Barone, Eugenio; Blarzino, Carla; Folgiero, Valentina; Caforio, Matteo; Valentini, Diletta; Villani, Alberto; Locatelli, Franco; Butterfield, D Allan; Head, Elizabeth; Perluigi, Marzia; Abisambra, Jose F; Di Domenico, Fabio.
Afiliação
  • Lanzillotta C; Department of Biochemical Sciences "A. Rossi Fanelli", Laboratory affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Sapienza University of Rome, Rome, Italy.
  • Zuliani I; Department of Biochemical Sciences "A. Rossi Fanelli", Laboratory affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Sapienza University of Rome, Rome, Italy.
  • Tramutola A; Department of Biochemical Sciences "A. Rossi Fanelli", Laboratory affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Sapienza University of Rome, Rome, Italy.
  • Barone E; Department of Biochemical Sciences "A. Rossi Fanelli", Laboratory affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Sapienza University of Rome, Rome, Italy.
  • Blarzino C; Department of Biochemical Sciences "A. Rossi Fanelli", Laboratory affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Sapienza University of Rome, Rome, Italy.
  • Folgiero V; Department of Pediatric Hematology/Oncology and of Cell and Gene Therapy, Bambino Gesù Children's Hospital, Rome, Italy.
  • Caforio M; Department of Biochemical Sciences "A. Rossi Fanelli", Laboratory affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Sapienza University of Rome, Rome, Italy; Department of Pediatric Hematology/Oncology and of Cell and Gene Therapy, Bambino Gesù Children's Hospital, Rome, Italy.
  • Valentini D; Pediatric and Infectious Disease Unit, Bambino Gesù Children's Hospital, Rome, Italy.
  • Villani A; Pediatric and Infectious Disease Unit, Bambino Gesù Children's Hospital, Rome, Italy.
  • Locatelli F; Department of Pediatric Hematology/Oncology and of Cell and Gene Therapy, Bambino Gesù Children's Hospital, Rome, Italy; Department of Pediatrics, Sapienza University of Rome, Rome, Italy.
  • Butterfield DA; Department of Chemistry, University of Kentucky, Lexington, KY, USA; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA.
  • Head E; Department of Pathology & Laboratory Medicine, University of California, Irvine, CA, USA.
  • Perluigi M; Department of Biochemical Sciences "A. Rossi Fanelli", Laboratory affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Sapienza University of Rome, Rome, Italy.
  • Abisambra JF; Department of Neuroscience and Center for Translational Research in Neurodegenerative Disease, University of Florida, Gainesville, FL, USA.
  • Di Domenico F; Department of Biochemical Sciences "A. Rossi Fanelli", Laboratory affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Sapienza University of Rome, Rome, Italy. Electronic address: fabio.didomenico@uniroma1.it.
Prog Neurobiol ; 196: 101892, 2021 01.
Article em En | MEDLINE | ID: mdl-32795489

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndrome de Down / EIF-2 Quinase / Inibidores de Proteínas Quinases / Resposta a Proteínas não Dobradas / Doença de Alzheimer Tipo de estudo: Prognostic_studies Limite: Adolescent / Adult / Aged / Aged80 / Animals / Child / Female / Humans / Male / Middle aged Idioma: En Revista: Prog Neurobiol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Itália

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndrome de Down / EIF-2 Quinase / Inibidores de Proteínas Quinases / Resposta a Proteínas não Dobradas / Doença de Alzheimer Tipo de estudo: Prognostic_studies Limite: Adolescent / Adult / Aged / Aged80 / Animals / Child / Female / Humans / Male / Middle aged Idioma: En Revista: Prog Neurobiol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Itália