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Life span extension by glucose restriction is abrogated by methionine supplementation: Cross-talk between glucose and methionine and implication of methionine as a key regulator of life span.
Zou, Ke; Rouskin, Silvia; Dervishi, Kevin; McCormick, Mark A; Sasikumar, Arjun; Deng, Changhui; Chen, Zhibing; Kaeberlein, Matt; Brem, Rachel B; Polymenis, Michael; Kennedy, Brian K; Weissman, Jonathan S; Zheng, Jiashun; Ouyang, Qi; Li, Hao.
Afiliação
  • Zou K; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158, USA.
  • Rouskin S; The State Key Laboratory for Artificial Microstructures and Mesoscopic Physics, School of Physics, Peking University, Beijing, China.
  • Dervishi K; Peking-Tsinghua Center for Life Sciences at Center for Quantitative Biology, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China.
  • McCormick MA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California Institute for Quantitative Biomedical Research and Howard Hughes Medical Institute, San Francisco, CA 94158, USA.
  • Sasikumar A; Harvard Medical School, Boston, MA 02115, USA.
  • Deng C; Department of Biochemistry and Molecular Biology, School of Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA.
  • Chen Z; Autophagy Inflammation and Metabolism Center of Biomedical Research Excellence, Albuquerque, NM 87131, USA.
  • Kaeberlein M; Buck Institute for Research on Aging, Novato, CA 94945, USA.
  • Brem RB; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158, USA.
  • Polymenis M; Department of Physical Therapy and Rehabilitation Science, University of California, San Francisco, San Francisco, CA 94158, USA.
  • Kennedy BK; Department of Pathology, University of Washington, Seattle, WA 98195, USA.
  • Weissman JS; Buck Institute for Research on Aging, Novato, CA 94945, USA.
  • Zheng J; Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA.
  • Ouyang Q; Buck Institute for Research on Aging, Novato, CA 94945, USA.
  • Li H; Departments of Biochemistry and Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Sci Adv ; 6(32): eaba1306, 2020 08.
Article em En | MEDLINE | ID: mdl-32821821

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Longevidade / Metionina Idioma: En Revista: Sci Adv Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Longevidade / Metionina Idioma: En Revista: Sci Adv Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos