Selective Targeting of the Hedgehog Signaling Pathway by PBM Nanoparticles in Docetaxel-Resistant Prostate Cancer.

Singh, Santosh Kumar; Gordetsky, Jennifer B; Bae, Sejong; Acosta, Edward P; Lillard, James W; Singh, Rajesh

Singh, Santosh Kumar; Gordetsky, Jennifer B; Bae, Sejong; Acosta, Edward P; Lillard, James W; Singh, Rajesh.

Afiliação

Singh SK; Department of Microbiology, Biochemistry and Immunology, Cancer Health Equity Institute, Morehouse School of Medicine, Atlanta, GA 30310, USA.
Gordetsky JB; Departments of Pathology and Urology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Bae S; Division of Preventive Medicine, University of Alabama at Birmingham School of Medicine, Birmingham, AL 35205, USA.
Acosta EP; Department of Pharmacology and Toxicology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Lillard JW; Department of Microbiology, Biochemistry and Immunology, Cancer Health Equity Institute, Morehouse School of Medicine, Atlanta, GA 30310, USA.
Singh R; Department of Microbiology, Biochemistry and Immunology, Cancer Health Equity Institute, Morehouse School of Medicine, Atlanta, GA 30310, USA.

Cells ; 9(9)2020 08 27.

Article em En | MEDLINE | ID: mdl-32867229

Assuntos

Resistencia a Medicamentos Antineoplásicos/efeitos dos fármacos; Proteínas Hedgehog/metabolismo; Nanopartículas/metabolismo; Neoplasias da Próstata/genética; Proliferação de Células; Humanos; Masculino; Neoplasias da Próstata/patologia; Transdução de Sinais

Palavras-chave

aptamer; drug transporter; nanoparticles; prostate cancer; thymoquinone

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Resistencia a Medicamentos Antineoplásicos / Proteínas Hedgehog / Nanopartículas Limite: Humans / Male Idioma: En Revista: Cells Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

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