Contributions of primary coordination ligands and importance of outer sphere interactions in UFsc, a de novo designed protein with high affinity for metal ions.

Kulesha, Alona; Yoon, Jennifer H; Chester, Cara; D'Souza, Areetha; Costeas, Christos; Makhlynets, Olga V

Kulesha, Alona; Yoon, Jennifer H; Chester, Cara; D'Souza, Areetha; Costeas, Christos; Makhlynets, Olga V.

Afiliação

Kulesha A; Department of Chemistry, Syracuse University, 111 College Place, Syracuse, NY 13244, United States.
Yoon JH; Department of Chemistry, Syracuse University, 111 College Place, Syracuse, NY 13244, United States.
Chester C; Department of Chemistry, Syracuse University, 111 College Place, Syracuse, NY 13244, United States.
D'Souza A; Department of Chemistry, Syracuse University, 111 College Place, Syracuse, NY 13244, United States.
Costeas C; Department of Chemistry, Syracuse University, 111 College Place, Syracuse, NY 13244, United States.
Makhlynets OV; Department of Chemistry, Syracuse University, 111 College Place, Syracuse, NY 13244, United States. Electronic address: ovmakhly@syr.edu.

J Inorg Biochem ; 212: 111224, 2020 11.

Article em En | MEDLINE | ID: mdl-32871348

Assuntos

Complexos de Coordenação/química; Metais/química; Proteínas/química; Calorimetria/métodos; Dicroísmo Circular; Histidina/química; Ligantes; Mutação; Proteínas/genética

Palavras-chave

De novo protein design; Isothermal titration calorimetry; Mag-Fura 2; Zinc binding

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas / Complexos de Coordenação / Metais Idioma: En Revista: J Inorg Biochem Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

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