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Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.
Chen, Ming-Huei; Raffield, Laura M; Mousas, Abdou; Sakaue, Saori; Huffman, Jennifer E; Moscati, Arden; Trivedi, Bhavi; Jiang, Tao; Akbari, Parsa; Vuckovic, Dragana; Bao, Erik L; Zhong, Xue; Manansala, Regina; Laplante, Véronique; Chen, Minhui; Lo, Ken Sin; Qian, Huijun; Lareau, Caleb A; Beaudoin, Mélissa; Hunt, Karen A; Akiyama, Masato; Bartz, Traci M; Ben-Shlomo, Yoav; Beswick, Andrew; Bork-Jensen, Jette; Bottinger, Erwin P; Brody, Jennifer A; van Rooij, Frank J A; Chitrala, Kumaraswamynaidu; Cho, Kelly; Choquet, Hélène; Correa, Adolfo; Danesh, John; Di Angelantonio, Emanuele; Dimou, Niki; Ding, Jingzhong; Elliott, Paul; Esko, Tõnu; Evans, Michele K; Floyd, James S; Broer, Linda; Grarup, Niels; Guo, Michael H; Greinacher, Andreas; Haessler, Jeff; Hansen, Torben; Howson, Joanna M M; Huang, Qin Qin; Huang, Wei; Jorgenson, Eric.
Afiliação
  • Chen MH; The Framingham Heart Study, National Heart, Lung and Blood Institute, Framingham, MA 01702, USA; Population Sciences Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, Framingham, MA 01702, USA.
  • Raffield LM; Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA.
  • Mousas A; Montreal Heart Institute, Montreal, QC H1T 1C8, Canada.
  • Sakaue S; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, Japan; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa 230-0045, Japan.
  • Huffman JE; Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, MA 02130, USA.
  • Moscati A; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Trivedi B; Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London E1 2AT, UK.
  • Jiang T; BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK.
  • Akbari P; BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK; MRC Biostatistics Unit, University of Cambridge, Cambridge CB2 0SR, UK; Human Genetics, Wellcome Sanger Institute, Hinxton CB10 1SA, UK; The National Institute for Heal
  • Vuckovic D; Human Genetics, Wellcome Sanger Institute, Hinxton CB10 1SA, UK.
  • Bao EL; Division of Hematology/Oncology, Boston Children's Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02446, USA.
  • Zhong X; Division of Genetic Medicine, Department of Medicine, Vanderbilt University, Nashville, TN 37232, USA.
  • Manansala R; Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, WI 53201, USA.
  • Laplante V; Département de Pharmacologie et Physiologie, Faculty of Medicine, Université de Montréal, Montreal, QC H3T 1J4, Canada.
  • Chen M; Center for Genetic Epidemiology, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA.
  • Lo KS; Montreal Heart Institute, Montreal, QC H1T 1C8, Canada.
  • Qian H; Department of Statistics and Operation Research, University of North Carolina, Chapel Hill, NC 27599, USA.
  • Lareau CA; Division of Hematology/Oncology, Boston Children's Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02446, USA.
  • Beaudoin M; Montreal Heart Institute, Montreal, QC H1T 1C8, Canada.
  • Hunt KA; Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London E1 2AT, UK.
  • Akiyama M; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa 230-0045, Japan; Department of Ocular Pathology and Imaging Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8581, Japan.
  • Bartz TM; Department of Biostatistics, University of Washington, Seattle, WA 98101, USA.
  • Ben-Shlomo Y; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol BS8 2PS, UK.
  • Beswick A; Translational Health Sciences, Musculoskeletal Research Unit, Bristol Medical School, University of Bristol, Bristol BS10 5NB, UK.
  • Bork-Jensen J; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen 2200, Denmark.
  • Bottinger EP; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Hasso-Plattner-Institut, Universität Potsdam, Potsdam 14469, Germany.
  • Brody JA; Department of Medicine, University of Washington, Seattle, WA 98101, USA.
  • van Rooij FJA; Department of Epidemiology, Erasmus University Medical Center Rotterdam, Rotterdam 3015, the Netherlands.
  • Chitrala K; Laboratory of Epidemiology and Population Science, National Institute on Aging/NIH, Baltimore, MD 21224, USA.
  • Cho K; Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, MA 02130, USA; Department of Medicine, Division on Aging, Brigham and Women's Hospital, Boston, MA 02115, USA; Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.
  • Choquet H; Division of Research, Kaiser Permanente Northern California, Oakland, CA 94612, USA.
  • Correa A; Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA.
  • Danesh J; BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK; Human Genetics, Wellcome Sanger Institute, Hinxton CB10 1SA, UK; The National Institute for Health Research Blood and Transplant Unit (NIHR BTRU) in Donor Health and Ge
  • Di Angelantonio E; BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK; The National Institute for Health Research Blood and Transplant Unit (NIHR BTRU) in Donor Health and Genomics, University of Cambridge, Cambridge CB2 0QQ, UK; Health Da
  • Dimou N; Section of Nutrition and Metabolism, International Agency for Research on Cancer, Lyon 69008, France; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina 45110, Greece.
  • Ding J; Department of Internal Medicine, Section of Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, NC 27101, USA.
  • Elliott P; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK; Imperial Biomedical Research Centre, Imperial College London and Imperial College NHS Healthcare Trust, London SW7 2AZ, UK; Medical Research Council-Public Health England Centre for Environment, Imperial Colleg
  • Esko T; Broad Institute of Harvard and MIT, Cambridge, MA 02446, USA.
  • Evans MK; Laboratory of Epidemiology and Population Science, National Institute on Aging/NIH, Baltimore, MD 21224, USA.
  • Floyd JS; Department of Medicine, University of Washington, Seattle, WA 98101, USA; Department of Epidemiology, University of Washington, Seattle, WA 98101, USA.
  • Broer L; Department of Internal Medicine, Erasmus University Medical Center Rotterdam, Rotterdam 3015, the Netherlands.
  • Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen 2200, Denmark.
  • Guo MH; Broad Institute of Harvard and MIT, Cambridge, MA 02446, USA; Department of Neurology, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Greinacher A; Institute for Immunology and Transfusion Medicine, University Medicine Greifswald, Greifswald 17475, Germany.
  • Haessler J; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen 2200, Denmark.
  • Howson JMM; BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK; Novo Nordisk Research Centre Oxford, Innovation Building, Old Road Campus, Oxford OX3 7FZ, UK.
  • Huang QQ; Human Genetics, Wellcome Sanger Institute, Hinxton CB10 1SA, UK.
  • Huang W; Department of Genetics, Shanghai-MOST Key Laboratory of Health and Disease Genomics, Chinese National Human Genome Center and Shanghai Industrial Technology Institute (SITI), Shanghai 201203, China.
  • Jorgenson E; Division of Research, Kaiser Permanente Northern California, Oakland, CA 94612, USA.
Cell ; 182(5): 1198-1213.e14, 2020 09 03.
Article em En | MEDLINE | ID: mdl-32888493
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mutação de Sentido Incorreto / Polimorfismo de Nucleotídeo Único / Povo Asiático / População Branca Tipo de estudo: Prognostic_studies / Systematic_reviews Limite: Humans Idioma: En Revista: Cell Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mutação de Sentido Incorreto / Polimorfismo de Nucleotídeo Único / Povo Asiático / População Branca Tipo de estudo: Prognostic_studies / Systematic_reviews Limite: Humans Idioma: En Revista: Cell Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos