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A bilateral tumor model identifies transcriptional programs associated with patient response to immune checkpoint blockade.
Chen, Ivy X; Newcomer, Kathleen; Pauken, Kristen E; Juneja, Vikram R; Naxerova, Kamila; Wu, Michelle W; Pinter, Matthias; Sen, Debattama R; Singer, Meromit; Sharpe, Arlene H; Jain, Rakesh K.
Afiliação
  • Chen IX; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114.
  • Newcomer K; Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA 02215.
  • Pauken KE; Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115.
  • Juneja VR; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115.
  • Naxerova K; Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115.
  • Wu MW; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115.
  • Pinter M; Center for Systems Biology, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114.
  • Sen DR; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114.
  • Singer M; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114.
  • Sharpe AH; Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115.
  • Jain RK; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02215.
Proc Natl Acad Sci U S A ; 117(38): 23684-23694, 2020 09 22.
Article em En | MEDLINE | ID: mdl-32907939

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Microambiente Tumoral / Imunoterapia / Neoplasias Mamárias Experimentais Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Microambiente Tumoral / Imunoterapia / Neoplasias Mamárias Experimentais Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article