N-butanol extract of Hedyotis diffusa protects transgenic Caenorhabditis elegans from Aß-induced toxicity.

DanQing, Li; YuJie, Guo; ChengPeng, Zhang; HongZhi, Du; Yi, Hong; BiSheng, Huang; Yan, Cao

DanQing, Li; YuJie, Guo; ChengPeng, Zhang; HongZhi, Du; Yi, Hong; BiSheng, Huang; Yan, Cao.

Afiliação

DanQing L; Key Laboratory of Education Ministry on Traditional Chinese Medicine Resource and Compound Prescription, Hubei University of Chinese Medicine, Wuhan, China.
YuJie G; Key Laboratory of Education Ministry on Traditional Chinese Medicine Resource and Compound Prescription, Hubei University of Chinese Medicine, Wuhan, China.
ChengPeng Z; Key Laboratory of Education Ministry on Traditional Chinese Medicine Resource and Compound Prescription, Hubei University of Chinese Medicine, Wuhan, China.
HongZhi D; Key Laboratory of Education Ministry on Traditional Chinese Medicine Resource and Compound Prescription, Hubei University of Chinese Medicine, Wuhan, China.
Yi H; Key Laboratory of Education Ministry on Traditional Chinese Medicine Resource and Compound Prescription, Hubei University of Chinese Medicine, Wuhan, China.
BiSheng H; Key Laboratory of Education Ministry on Traditional Chinese Medicine Resource and Compound Prescription, Hubei University of Chinese Medicine, Wuhan, China.
Yan C; Key Laboratory of Education Ministry on Traditional Chinese Medicine Resource and Compound Prescription, Hubei University of Chinese Medicine, Wuhan, China.

Phytother Res ; 35(2): 1048-1061, 2021 Feb.

Article em En | MEDLINE | ID: mdl-32924204

Assuntos

1-Butanol/química; Doença de Alzheimer/tratamento farmacológico; Peptídeos beta-Amiloides/efeitos dos fármacos; Hedyotis/química; Medicina Tradicional Chinesa/métodos; Doenças Neurodegenerativas/tratamento farmacológico; Estresse Oxidativo/efeitos dos fármacos; Extratos Vegetais/química; Animais; Animais Geneticamente Modificados; Caenorhabditis elegans; Proteínas de Caenorhabditis elegans; Modelos Animais de Doenças; Humanos

Palavras-chave

Alzheimer's disease; Caenorhabditis elegans; Hedyotis diffusa; amyloid beta-peptide 1-42; insulin/insulin-like growth factor-1 signaling pathway

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Extratos Vegetais / Peptídeos beta-Amiloides / Estresse Oxidativo / Doenças Neurodegenerativas / 1-Butanol / Hedyotis / Doença de Alzheimer / Medicina Tradicional Chinesa Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Phytother Res Assunto da revista: TERAPIAS COMPLEMENTARES Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

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