[Quality assurance in diagnostic in situ hybridization-experience of QuIP]. / Qualitätssicherung in der diagnostischen In-situ-Hybridisierung Erfahrungen der QuIP.
Pathologe
; 41(6): 614-620, 2020 Nov.
Article
em De
| MEDLINE
| ID: mdl-32945916
ABSTRACT
The Quality Assurance Initiative Pathology (QuIP) gives pathologists the opportunity to check the methodological processes of immunohistological and molecular diagnostics in a result-oriented manner and obtain a certificate reflecting the quality. For in situ hybridization (ISH), 5 round robin tests were organized in 2019, two recurrent (HER2-ISH gastric carcinomas and HER2-ISH breast carcinomas) and three prototypical (ROS1-NSCLC, ALK1-NSCLC, NTRK). The different round robin tests, which were provided by QuIP, are based on the development in diagnostics and the importance of the therapeutic relevance of the molecules which are tested. The results of the round robin tests in 2019 showed a sensitivity of at least 94.4%, a specificity of at least 96.6%, and a success rate of 85-99%. This reflected the high standard of quality of the round robin test and the participating institutes.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Garantia da Qualidade dos Cuidados de Saúde
/
Neoplasias da Mama
/
Hibridização In Situ
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
De
Revista:
Pathologe
Ano de publicação:
2020
Tipo de documento:
Article