Early life stress from allergic dermatitis causes depressive-like behaviors in adolescent male mice through neuroinflammatory priming.

Hashimoto, Okito; Kuniishi, Hiroshi; Nakatake, Yuko; Yamada, Mitsuhiko; Wada, Keiji; Sekiguchi, Masayuki

Hashimoto, Okito; Kuniishi, Hiroshi; Nakatake, Yuko; Yamada, Mitsuhiko; Wada, Keiji; Sekiguchi, Masayuki.

Afiliação

Hashimoto O; Department of Degenerative Neurological Diseases, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan. Electronic address: okito_hashimoto@ncnp.go.jp.
Kuniishi H; Department of Degenerative Neurological Diseases, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan; Department of Neuropsychopharmacology, National Institute of Mental Health, National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan.
Nakatake Y; Department of Neuropsychopharmacology, National Institute of Mental Health, National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan; Laboratory of Pharmacology and Therapeutics, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Chiba, Japan.
Yamada M; Department of Neuropsychopharmacology, National Institute of Mental Health, National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan.
Wada K; Department of Degenerative Neurological Diseases, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan.
Sekiguchi M; Department of Degenerative Neurological Diseases, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan.

Brain Behav Immun ; 90: 319-331, 2020 11.

Article em En | MEDLINE | ID: mdl-32950622

Assuntos

Experiências Adversas da Infância; Dermatite; Animais; Criança; Pré-Escolar; Citocinas/metabolismo; Depressão; Hipocampo/metabolismo; Humanos; Cinurenina; Lipopolissacarídeos; Masculino; Camundongos; Camundongos Endogâmicos C57BL

Palavras-chave

Abnormal kynurenine metabolism; Allergic dermatitis; Depression; Early life stress; Microglia; Neuroinflammation; Neuroinflammatory priming

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dermatite / Experiências Adversas da Infância Tipo de estudo: Etiology_studies Limite: Animals / Child / Child, preschool / Humans / Male Idioma: En Revista: Brain Behav Immun Assunto da revista: ALERGIA E IMUNOLOGIA / CEREBRO / PSICOFISIOLOGIA Ano de publicação: 2020 Tipo de documento: Article

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