Deep learning based prediction of reversible HAT/HDAC-specific lysine acetylation.

Yu, Kai; Zhang, Qingfeng; Liu, Zekun; Du, Yimeng; Gao, Xinjiao; Zhao, Qi; Cheng, Han; Li, Xiaoxing; Liu, Ze-Xian

Yu, Kai; Zhang, Qingfeng; Liu, Zekun; Du, Yimeng; Gao, Xinjiao; Zhao, Qi; Cheng, Han; Li, Xiaoxing; Liu, Ze-Xian.

Afiliação

Yu K; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.
Zhang Q; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.
Liu Z; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.
Du Y; School of Life Sciences, Zhengzhou University, Zhengzhou 450001, China.
Gao X; Division of Molecular and Cell Biophysics, Hefei National Science Center for Physical Sciences at the Microscale, Anhui Key Laboratory of Cellular Dynamics and Chemical Biology, School of Life Sciences, University of Science and Technology of the China, Hefei 230027, China.
Zhao Q; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.
Cheng H; School of Life Sciences, Zhengzhou University, Zhengzhou 450001, China.
Li X; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.
Liu ZX; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.

Brief Bioinform ; 21(5): 1798-1805, 2020 09 25.

Article em En | MEDLINE | ID: mdl-32978618

Assuntos

Aprendizado Profundo; Histona Desacetilases/metabolismo; Lisina/metabolismo; Neoplasias/metabolismo; Acetilação; Conjuntos de Dados como Assunto; Humanos; Internet; Neoplasias/enzimologia; Neoplasias/patologia

Palavras-chave

HAT/HDAC; acetylation; cancer mutation; deep learning; prediction

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Aprendizado Profundo / Histona Desacetilases / Lisina / Neoplasias Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Brief Bioinform Assunto da revista: BIOLOGIA / INFORMATICA MEDICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China

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